4-Tolylboronic acid Chemical Properties

Melting point:

256-263 °C(lit.)

Boiling point:

275.2±33.0 °C(Predicted)

Density 

1.10±0.1 g/cm3(Predicted)

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

DMSO (Slightly), Methanol (Slightly)

pka

8.84±0.10(Predicted)

form 

Crystalline Powder

color 

Off-white

Water Solubility 

It is soluble in water.

BRN 

2935970

InChI

InChI=1S/C7H9BO2/c1-6-2-4-7(5-3-6)8(9)10/h2-5,9-10H,1H3

InChIKey

BIWQNIMLAISTBV-UHFFFAOYSA-N

SMILES

B(C1=CC=C(C)C=C1)(O)O

CAS DataBase Reference

5720-05-8(CAS DataBase Reference)

NIST Chemistry Reference

P-methylbenzeneboronic acid(5720-05-8)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36-37/39

WGK Germany 

3

RTECS 

XS7400000

HazardClass 

IRRITANT

HS Code 

29319090

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

4-Tolylboronic acid Usage And Synthesis

Chemical Properties

white to light yellow crystal powder

Uses

suzuki reaction

Uses

4-Methylbenzeneboronic acid, is a commonly used chemical in Suzuki coupling reactions. It is also used as an intermediate in pharmaceutical industry

Uses

Reagent used for

• Palladium (Pd)-catalyzed direct arylation
• Direct Palladium(II)-Catalyzed Synthesis
• Palladium-catalyzed arylation by Suzuki-Miyaura cross-coupling in water
• Cyclopalladation
• Tandem-type Pd(II)-catalyzed oxidative Heck reaction and intramolecular C-H amidation sequence
• Ruthenium catalyzed direct arylation
• Rhodium-catalyzed asymmetric conjugate addition
• Ligand-free copper-catalyzed cross-coupling reactions
• Regioselective arylation and alkynylation by Suzuki-Miyaura and Sonogashira cross-coupling reactions
• Ligand-free Suzuki, Sonogashira, and Heck cross-coupling reactions

• Catalysts for Suzuki-Miyaura cross-coupling of aryl bromides
• Recyclable Palladium nanoparticle catalysts immobilized by click ionic copolymers as for Suzuki-Miyaura cross-coupling reactions in water

4-Tolylboronic acid(5720-05-8)Related Product Information

• 3-Nitrophenylboronic acid
• 2-Phenylphenol
• Zinc borate
• Methylboronic acid
• 4-Bromomethylbenzoic acid
• (4-METHOXYPHENYL)-BORANE
• Phenylboronic acid
• 4-Methoxyphenylboronic acid
• Triphenylphosphine
• Chlorodimethylphenylsilane
• Tosyl chloride
• p-Tolualdehyde
• 3,5-Dimethylphenylboronic acid
• p-Toluenesulfonic acid
• p-Toluic acid
• Xylene
• 4-Aminophenylboronic acid
• p-Tolunitrile