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ChemicalBook >  Product Catalog >  Pharmaceutical intermediates >  Heterocyclic compound >  Pyridine compound >  Pyridine derivatives >  1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one

1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one

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1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one Basic information

Product Name:
1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one
Synonyms:
  • 1,2,4-TRIAZOLO-[4,3-A]PYRIDINE-3(2H)-ONE
  • 1,2,4-TRIAZOLE(4,3)PYRIDIN-3-(2H)-ONE
  • 1,2,4-TRIAZOL-(4,3-A)-PYRIDINE 3 (2H)-ONE
  • 1,2,4-Triazolopyridin-3-one
  • 3-HYDROXYTRIAZOLO[4,3-A]PYRIDINE
  • 3-HYDROXY-1,2,4-TRIAZOLO[4,3-A]PYRIDINE
  • 1,2,4-Triazole-(4,3-alpha)pyri
  • Trazodone Impurity 15
CAS:
6969-71-7
MF:
C6H5N3O
MW:
135.12
EINECS:
230-191-8
Product Categories:
  • Heterocycles
  • intermediate for some organic synthesis
  • APIs & Intermediate
  • Pyrimidine
  • Pyridines
  • Fused Ring Systems
Mol File:
6969-71-7.mol
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1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one Chemical Properties

Melting point:
231°C
Density 
1.51±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
pka
7.86±0.20(Predicted)
BRN 
607433
InChIKey
LJRXNXBFJXXRNQ-UHFFFAOYSA-N
CAS DataBase Reference
6969-71-7(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
HS Code 
29339900

MSDS

  • Language:English Provider:ALFA
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1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one Usage And Synthesis

Chemical Properties

Beige Solid

Uses

1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one was used to prepare a congener of Trazodone (T718500) which was found to be a potent and selective inhibitor of synaptosomal uptake of 5-hydroxytryptamine.

Synthesis Reference(s)

Journal of Medicinal Chemistry, 28, p. 1394, 1985 DOI: 10.1021/jm00148a004

1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one Preparation Products And Raw materials

Raw materials

1,2,4-Triazolo[4,3-a]pyridin-3(2H)-oneSupplier

Yangzhou Prince Chemical Co., Ltd Gold
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