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thonningianin A

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thonningianin A Basic information

Product Name:
thonningianin A
Synonyms:
  • thonningianin A
  • Pinocembrin dihydrochalcone 7-O-[3''-O-galloyl-4'',6''-hexahydroxydiphenoyl]-beta-D-glucoside
  • 1-Propanone, 1-[4-[[4,6-O-[[(1S)-4,4',5,5',6,6'-hexahydroxy[1,1'-biphenyl]-2,2'-diyl]dicarbonyl]-3-O-(3,4,5-trihydroxybenzoyl)-β-D-glucopyranosyl]oxy]-2,6-dihydroxyphenyl]-3-phenyl-
  • superoxide,inhibit,Apoptosis,cell,Fe2+,metal,chelation,sub-G1,Inhibitor,ions,Thonningianin A,scavenging,HepG-2,antioxidant
  • Thonningianins A
  • Thonningianin A/B
  • Thonningianin A, 10 mM in DMSO
  • (11aR,13S,14R,15R,15aR)-13-(3,5-Dihydroxy-4-(3-phenylpropanoyl)phenoxy)-2,3,4,5,6,7,14-heptahydroxy-9,17-dioxo-9,11,11a,13,14,15,15a,17-octahydrodibenzo[g,i]pyrano[3,2-b][1,5]dioxacycloundecin-15-yl 3,4,5-trihydroxybenzoate
CAS:
271579-11-4
MF:
C42H34O21
MW:
874.71
Mol File:
271579-11-4.mol
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thonningianin A Chemical Properties

Boiling point:
1364.1±65.0 °C(Predicted)
Density 
1.89±0.1 g/cm3(Predicted)
storage temp. 
4°C, protect from light
solubility 
Soluble in DMSO
form 
Solid
pka
6.80±0.40(Predicted)
color 
White to yellow
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thonningianin A Usage And Synthesis

Uses

Thonningianin A, an ellagitannin, is isolated from the methanolic extract of the African medicinal herb, Thonningia sanguinea. The antioxidant properties of Th A involve radical scavenging, anti-superoxide formation and metal chelation. Anti-cancer activities[1][2].

Definition

ChEBI: Thonningianin A is a tannin. It has a role as a metabolite.

References

[1] Gyamfi MA, et al. Antioxidant properties of Thonningianin A, isolated from the African medicinal herb, Thonningia sanguinea. Biochem Pharmacol. 2002 May 1;63(9):1725-37. DOI:10.1016/s0006-2952(02)00915-2
[2] Zhang TT, et al. Effects of thonningianin A in natural foods on apoptosis and cell cycle arrest of HepG-2 human hepatocellular carcinoma cells. Food Funct. 2015 Aug;6(8):2588-97. DOI:10.1039/c5fo00388a

thonningianin ASupplier

Chengdu Biopurify Phytochemicals Ltd.
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