N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid
N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid Basic information
- Product Name:
- N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid
- Synonyms:
-
- N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid
- 2-PyridinecarboxaMide, N-(2-aMinoethyl)-5-chloro-, Monohydrochloride
- Ro 19-6327/001
- TeMpiuM
- JMFKTFLARGGXCC-UHFFFAOYSA-N
- N-(2-Aminoethyl)-5-chloro-2-pyridinecarboxamide hydrochloride
- N-(2-Aminoethyl)-5-chlor-2-pyridincarbox
- ichemia,Lazabemide,DOPAC,MAO,radical generation,Ro 19-6327,disease,alzheimer′s,Inhibitor,inhibit,Lazabemide hydrochloride,Monoamine Oxidase,smoking cessation,parkinson
- CAS:
- 103878-83-7
- MF:
- C8H10ClN3O.HCl
- MW:
- 0
- Product Categories:
-
- Monoamine Oxidase
- Mol File:
- 103878-83-7.mol
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N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid Chemical Properties
- Melting point:
- 193-195°
- storage temp.
- Desiccate at RT
- solubility
- Soluble to 100 mM in water and to 100 mM in DMSO
- form
- Powder
- pka
- 8.9(at 25℃)
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N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid Usage And Synthesis
Uses
Treatment of Alzheimer’s disease.
Uses
Lazabemide Hydrochloride is a reversible and selective inhibitor of MAO-A and MAO-B, both of which oxidatively deaminate neurotransmitter and xenobiotic amines.
Definition
ChEBI: Lazabemide hydrochloride is a pyridinecarboxamide.
brand name
Tempium (Hoffmann-LaRoche).
Biological Activity
Selective, reversible monoamine oxidase B (MAO-B) inhibitor (IC 50 values are 0.03 and > 100 μ M for MAO-B and MAO-A respectively). Inhibits monoamine uptake at high concentrations (IC 50 values are 86, 123 and > 500 μ M for noradrenalin, serotonin and dopamine uptake respectively).
storage
Desiccate at RT
N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochloridSupplier
3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel
- 821-50328103-801 18930552037
- 3bsc@sina.com
Beijing HuaMeiHuLiBiological Chemical
- Tel
- 010-56205725
- waley188@sohu.com
Shanghai JiYi Biotechnology Co. Ltd.
- Tel
- 13621943973
- sales@shjiyipharmatech.com
ShangHai Biochempartner Co.,Ltd
- Tel
- 177-54423994 17754423994
- 2853530910@QQ.com
MQ (shanghai) Pharmaceuticals Co., Ltd.
- Tel
- 13761635123
- 1014988033@qq.com
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N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid(103878-83-7)Related Product Information
- Methylamine hydrochloride
- Cysteamine hydrochloride
- 1-(5-CHLOROPYRIDIN-2-YL)METHANAMINE
- METHYLPYRIDIN-2-YLMETHYLAMINE DIHYDROCHLORIDE
- 5-CHLORO-2-FORMYLPYRIDINE
- LAZABEMIDE
- 5-Chloropyridine-2-carboxamide
- PYRIDINE-2-CARBOXYLIC ACID (2-AMINO-ETHYL)-AMIDE
- N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid