Scillascillin
Scillascillin Basic information
- Product Name:
- Scillascillin
- Synonyms:
-
- (R)-5,7-Dihydroxyspiro[2H-1-benzopyran-3(4H),5'(6'H)-cyclobuta[f][1,3]benzodioxol]-4-one
- Scillascillin
- Scylin
- Spiro[2H-1-benzopyran-3(4H),5'(6'H)-cyclobuta[f][1,3]benzodioxol]-4-one, 5,7-dihydroxy-, (3R)-
- CAS:
- 52706-07-7
- MF:
- C17H12O6
- MW:
- 312.27
- Mol File:
- 52706-07-7.mol
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Scillascillin Chemical Properties
- Boiling point:
- 607.3±55.0 °C(Predicted)
- Density
- 1.69 g/cm3
- pka
- 7.11±0.20(Predicted)
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Scillascillin Usage And Synthesis
Uses
Scillascillin (compound 10) is a homoisoflavanone. Scillascillin can be isolated from S. scilloides. Scillascillin shows anticancer activity towards MCF-7 (breast cancer) and DU-145 (prostate cancer) cells with the IC50 of 9.59 and 11.32 ug/ml, respectively[1][2].
References
[1] Yoichiro Nishida, et al. A new homostilbene and two new homoisoflavones from the bulbs of Scilla scilloides. Chem Pharm Bull (Tokyo). 56, 7. DOI:10.1248/cpb.56.1022
[2] Chinthala Y, et al. Anticancer Active Homoisoflavone from the Underground Bulbs of Ledebouria hyderabadensis. Pharmacognosy Res. 2014;6(4):303-305. DOI:10.4103/0974-8490.138272
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