BML-259
BML-259 Basic information
- Product Name:
- BML-259
- Synonyms:
-
- BML-259
- CAY10554
- 2-phenyl-N-(5-propan-2-yl-1,3-thiazol-2-yl)acetamide
- Benzeneacetamide, N-[5-(1-methylethyl)-2-thiazolyl]-
- BML-259,protein,p53,CDK,death,disease,neurotoxicity,cell,Inhibitor,inhibit,Cyclin dependent kinase,Alzheimer's
- CAS:
- 267654-00-2
- MF:
- C14H16N2OS
- MW:
- 260.35
- Mol File:
- 267654-00-2.mol
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BML-259 Chemical Properties
- Melting point:
- 150-152℃
- storage temp.
- RT
- solubility
- Soluble in DMSO (up to 25 mg/ml).
- form
- White solid.
- color
- white
- Stability:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
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BML-259 Usage And Synthesis
Description
BML-259 (267654-00-2) is a potent inhibitor of Cdk5/p25 (IC50 = 64 nM) and Cdk2 (IC50 = 98nM).1
Definition
ChEBI: 2-phenyl-N-(5-propan-2-yl-2-thiazolyl)acetamide is a member of acetamides.
References
1) Helal et al. (2004) Discovery and SAR of 2-aminothiazole inhibitors of cyclin-dependent kinase 5/p25 as a potential treatment for Alzheimer’s disease; Bioorg. Med. Chem. Lett. 14 5521
BML-259Supplier
BOC Sciences
- Tel
- 16314854226
- info@bocsci.com
Shanghai EFE Biological Technology Co., Ltd.
- Tel
- 021-65675885 18964387627
- info@efebio.com
Shanghai Hongye Biotechnology Co. Ltd
- Tel
- 400-9205774
- sales@glpbio.cn
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
- Tel
- 18818260767
- sales@chemegen.com
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd
- Tel
- 15317229551
- 15151849396@163.com