Basic information Safety Supplier Related

3'-Hydroxypterostilbene

Basic information Safety Supplier Related

3'-Hydroxypterostilbene Basic information

Product Name:
3'-Hydroxypterostilbene
Synonyms:
  • 3'-Hydroxypterostilbene
  • 3'-H518-82-1ydroxypterostilbene
  • 4-[(E)-2-(3,5-Dimethoxyphenyl)ethenyl]benzene-1,2-diol
  • 4-[(E)-2-(3,5-Dimethoxyphenyl)vinyl]benzene-1,2-diol
  • 4-[(1E)-2-(3,5-Dimethoxyphenyl)vinyl]benzene-1,2-diol
  • 4-[2-(3,5-dimethoxyphenyl)ethenyl]benzene-1,2-diol
  • 1,2-Benzenediol,4-[(1E)-2-(3,5-dimethoxyphenyl)ethenyl]-
  • 3'-HPT
CAS:
475231-21-1
MF:
C16H16O4
MW:
272.3
EINECS:
610-361-1
Product Categories:
  • reference substance
Mol File:
475231-21-1.mol
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3'-Hydroxypterostilbene Chemical Properties

Melting point:
112-115 °C
Boiling point:
469.7±45.0 °C(Predicted)
Density 
1.251±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
9.51±0.10(Predicted)
color 
White to Off-White
Stability:
Light Sensitive
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3'-Hydroxypterostilbene Usage And Synthesis

Uses

(E)?-?4-?(3,?5-?Dimethoxystyryl)?benzene-?1,?2-?diol can be used in biological study of evaluation of 90 day repeated dose oral toxicity and reproductive?/developmental toxicity of 3''-?hydroxypterostilbene in experimental animals.

in vivo

3'-Hydroxypterostilbene (10 mg/kg; i.p. once per day for 15 days) strongly inhibits tumor growth in vivo[1].

Animal Model:3-4 week old BALB/c nude mice with human colorectal carcinoma COLO 205 tumor xenografts[1]
Dosage:10 mg/kg
Administration:Intraperitoneal injection; 10 mg/kg once per day for 15 days
Result:Significantly inhibited tumor volume and tumor weight after 15 days treatment compared with the pterostilbene-treated mice, and decreased the protein levels of COX-2, MMP-9, VEGF, cyclin D1 and pro-caspase-3 in mice.

3'-HydroxypterostilbeneSupplier

Wuhan Wei Shunda Technology Development Co., Ltd.
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86-027-88774375
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Shandong Xiya Chemical Co., Ltd
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4009903999 13355009207
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Dalian Meilun Biotech Co., Ltd.
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0411-62910999 13889544652
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ShangHai YuanYe Biotechnology Co., Ltd.
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021-61312847 13636370518
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shyysw007@163.com
Chengdu Ai Keda Chemical Technology Co., Ltd.
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4008-755-333 18080918076
Email
800078821@qq.com
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