Baicalin-7-diglucoside
Baicalin-7-diglucoside Basic information
- Product Name:
- Baicalin-7-diglucoside
- Synonyms:
-
- 5,6-Dihydroxy-4-oxo-2-phenyl-4H-chromen-7-yl 6-O-β-D-glucopyranos yl-β-D-glucopyranoside
- Baicalein 7-diglucoside
- Baicalin-7-diglucoside
- 7-[(6-O-beta-D-Glucopyranosyl-beta-D-glucopyranosyl)oxy]-5,6-dihydroxy-2-phenyl-4H-1-benzopyran-4-one
- Baicalein 7-O-beta-gentiobioside
- Baicalein 7-O-diglucoside
- Baicalein-7-O-gentiobioside
- Oroxin B, 98%, from Oroxylum indicum
- CAS:
- 114482-86-9
- MF:
- C27H30O15
- MW:
- 594.52
- Product Categories:
-
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- Mol File:
- 114482-86-9.mol
Baicalin-7-diglucoside Chemical Properties
- Boiling point:
- 957.5±65.0 °C(Predicted)
- Density
- 1.76
- storage temp.
- 4°C, protect from light
- solubility
- Soluble in methanol and water
- form
- powder
- pka
- 5.91±0.40(Predicted)
- color
- Yellowish
- InChIKey
- HAYLVXFWJCKKDW-WEYZNFCFNA-N
Safety Information
- Safety Statements
- 24/25
- HS Code
- 29389090
Baicalin-7-diglucoside Usage And Synthesis
Chemical Properties
Soluble in methanol, ethanol, water, etc., insoluble in petroleum ether and chloroform. Derived from Oroxylum indicum, Bignoniaceae
Uses
Oroxin B is a component of the seed of O. (oroxylum) indicum and is used in traditional Chinese medicine for antiinflammatory, analgesic and other functions. It also has been observed to selectively induce tumor-suppressive ER stress and inhibits tumor-adaptive ER stress in B-lymphoma cells attenuating tumor growth.
in vivo
Oroxin B (30 mg/kg, i.p., 28 days) induces malignant lymphoma cell ER stress, and inhibits tumor growth in human lymphoma cell (Raji cell) xenograft model[2].
Oroxin B (160 μM of 10 μL, injected into the knee joints of mice) protects articular cartilage in destabilized medial meniscus (DMM) induced mice OA[3].
Oroxin B (200 mg/kg/day, oral gavage) relieves hepatic inflammation and inhibits MAFLD progression in HFD-fed rats[4].
| Animal Model: | Human lymphoma cell (Raji cell) xenograft model[2] |
| Dosage: | 30 mg/kg |
| Administration: | i.p., 28 days |
| Result: | Induced malignant lymphoma cell ER stress. Inhibited tumor growth. Prolonged overall survival of tumor-bearing mice. |
| Animal Model: | HFD-fed rats[4] |
| Dosage: | 200 mg/kg/day |
| Administration: | oral gavage |
| Result: | Reduced the levels of plasma lipids, LPS, IL-6, and TNF-α. Inhibited liver fibrosis by reducing collagen deposition. |
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Baicalin-7-diglucoside(114482-86-9)Related Product Information
- Oroxylin A
- CPNQ
- Vitamin B series
- Chrysin
- hydroxygenkwanin
- 4',5-DIHYDROXY-7-METHOXYFLAVONE
- Oroxylin A-7-O-glucuronide
- MEDICAGOL
- Naringenin 7-O-β-D-Glucuronide (Mixture of Diastereomers)
- BAICALEIN 7-O-B-D-GLUCOPYRANOSIDE (BAICALIN)
- GARDENIN B
- Naringenin
- MOSLOFLAVONE
- Quercetin-7-O-β-D-glucopyranoside
- PONCIRIN
- Chrysin-7-O-Beta-D-glucoronide
- 2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one
- CARDAMONIN