Basic information Safety Supplier Related

1-(3-Chlorophenyl)-4-(3-chloropropyl)piperazine hydrochloride

Basic information Safety Supplier Related

1-(3-Chlorophenyl)-4-(3-chloropropyl)piperazine hydrochloride Basic information

Product Name:
1-(3-Chlorophenyl)-4-(3-chloropropyl)piperazine hydrochloride
Synonyms:
  • CCP HCL
  • LABOTEST-BB LT00138222
  • 1-(3-Chlorophenyl)-4-(3-chloropropyl)piperazine monohydrochlorid
  • Trazodone BP IMP F
  • Trazodone EP Impurity F
  • 1-(3-CHLOROPHENY)-4-(3-CHLOROPROPYL) PIPERAZINE HYDROCHLORIDE
  • 1-(3-CHLOROPHENYL)-4-(3-CHLOROPROPYL) PIPERAZINE HCL
  • 1-[4-(3-Chlorophenyl)piperazin-1-yl]-3-chloropropane Hydrochloride
CAS:
52605-52-4
MF:
C13H19Cl3N2
MW:
309.66
EINECS:
258-038-0
Product Categories:
  • Building Blocks
  • Halogenated Heterocycles
  • Piperidines, Piperidones, Piperazines
  • Piperazine derivates
  • Heterocyclic Building Blocks
  • Piperazines
  • Aromatics
  • Heterocycles
  • C12 to C14
  • Building Blocks
  • C13
  • Chemical Synthesis
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
  • PiperazinesHeterocyclic Building Blocks
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
Mol File:
52605-52-4.mol
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1-(3-Chlorophenyl)-4-(3-chloropropyl)piperazine hydrochloride Chemical Properties

Melting point:
198-203 °C(lit.)
Boiling point:
147℃[at 101 325 Pa]
vapor pressure 
0Pa at 25℃
storage temp. 
2-8°C
solubility 
DMSO (Slightly, Heated), Methanol (Slightly, Heated)
form 
powder to crystal
color 
White to Light yellow
Water Solubility 
3.9g/L at 28℃
InChIKey
JVLRNANYLVRULL-UHFFFAOYSA-N
LogP
0.301 at 28℃
CAS DataBase Reference
52605-52-4(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-20/21/22
Safety Statements 
26-37/39-24/25
WGK Germany 
3
10-21
HS Code 
2933599550

MSDS

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1-(3-Chlorophenyl)-4-(3-chloropropyl)piperazine hydrochloride Usage And Synthesis

Chemical Properties

Off-White Solid

Uses

1-(3-Chlorophenyl)-4-(3-chloropropyl)piperazine hydrochloride is an arylpiperazine compound which is an important intermediate in the preparation of various pharmaceuticals, such as Trazodone (T718500), used to treat depression and post-traumatic stress.

General Description

1-(3-Chlorophenyl)-4-(3-chloropropyl)piperazine monohydrochloride is present as impurity in nefazodone hydrochloride (pharmaceutical formulation). Synthesis of 1-(3-chlorophenyl)-4-(3-chloropropyl)piperazine monohydrochloride is reported.

Flammability and Explosibility

Not classified

1-(3-Chlorophenyl)-4-(3-chloropropyl)piperazine hydrochloride Preparation Products And Raw materials

Raw materials

1-(3-Chlorophenyl)-4-(3-chloropropyl)piperazine hydrochlorideSupplier

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