Basic information Safety Supplier Related

SPDP-PEG8-acid

Basic information Safety Supplier Related

SPDP-PEG8-acid Basic information

Product Name:
SPDP-PEG8-acid
Synonyms:
  • SPDP-PEG8-acid
  • SDPD-PEG8-COOH
  • Opss-peg(8)-cooh
  • SPDP-PEG8-COOH
  • Propanoic acid, 3-[[25-oxo-27-(2-pyridinyldithio)-3,6,9,12,15,18,21-heptaoxa-24-azaheptacos-1-yl]oxy]-
CAS:
1334177-96-6
MF:
C27H46N2O11S2
MW:
638.79094
Product Categories:
  • peg
Mol File:
1334177-96-6.mol
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SPDP-PEG8-acid Usage And Synthesis

Description

SPDP-PEG8-acid is a PEG linker containing SPDP crosslinker and carboxylic acid moieties. SPDP is reactive toward thiol groups and contains a cleavable disulfide bond. Its membrane permeability allows for intracellular crosslinking reactions. The terminal caboxylic acid can react with primary amines in the presence of activators such as EDC and HATU to form stable amide bonds. The hydrophilic properties of the PEG linkers increase compound solubility in aqueous media.

SPDP-PEG8-acidSupplier

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