RHEIN-8-GLUCOSIDE
RHEIN-8-GLUCOSIDE Basic information
- Product Name:
- RHEIN-8-GLUCOSIDE
- Synonyms:
-
- RHEIN-8-GLUCOSIDE
- Rhein-5-O-β-D-glucopyranoside
- Rhein-8-O-glucopyranoside
- Rhein 8-O-glucoside
- Glucorein
- 8-Glucosidorhein-9-anthrone
- 5-(beta-D-Glucopyranosyloxy)-9,10-dihydro-4-hydroxy-9,10-dioxo-2-anthracenecarboxylic acid
- Rhein 8Glucoside,Inhibitor,Rhein 8-Glucoside,Rhein 8 Glucoside,inhibit
- CAS:
- 34298-86-7
- MF:
- C21H18O11
- MW:
- 446.36
- Product Categories:
-
- Anthraquinones, Hydroquinones and Quinones
- Mol File:
- Mol File
RHEIN-8-GLUCOSIDE Chemical Properties
- Melting point:
- >245°C (dec.)
- Boiling point:
- 854.4±65.0 °C(Predicted)
- Density
- 1.736±0.06 g/cm3(Predicted)
- storage temp.
- Hygroscopic, Refrigerator, under inert atmosphere
- solubility
- DMSO (Slightly)
- pka
- 3.19±0.20(Predicted)
- form
- Solid
- color
- Yellow
RHEIN-8-GLUCOSIDE Usage And Synthesis
Uses
Rhein 8-Glucoside has been seen to exhibit cytotoxic and DNA-damaging properties towards tumor and normal human cells. In addition it has been shown to be an inhibitor of PTP1B (Human Protein Tyrosine Kinase 1B) in vitro. It is an analog of Rhein (R318500) which is found in the free state and as glucoside in Rheum spp, Polygonaceae (rhubarb) and in Senna leaves. It is a potential antioxidant resource: endophytic fungi from medicinal plants.
Uses
Rhein 8-Glucoside has been seen to exhibit cytotoxic and DNA-damaging properties towards tumor and normal human cells. In addition it has been shown to be an inhibitor of PTP1B (Human Protein Tyrosine Kinase 1B) in vitro. It is an analog of Rhein (318500) which is found in the free state and as glucoside in Rheum spp, Polygonaceae (rhubarb) and in Senna leaves. It is a potential antioxidant resour ce: endophytic fungi from medicinal plants.
General Description
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG
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