1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol Chemical Properties

Melting point:

138 °C

Boiling point:

480.9±45.0 °C(Predicted)

Density 

1.214±0.06 g/cm3(Predicted)

pka

10.00±0.15(Predicted)

form 

Solid

color 

Off-white to light yellow

1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol Usage And Synthesis

Uses

(±)-N-Methylcoclaurine is a selective α2-adrenoceptor antagonist[1].

References

[1] H H Pauli, et al. Molecular cloning and functional heterologous expression of two alleles encoding (S)-N-methylcoclaurine 3'-hydroxylase (CYP80B1), a new methyl jasmonate-inducible cytochrome P-450-dependent mono-oxygenase of benzylisoquinoline alkaloid biosynthesis. Plant J. 1998 Mar;13(6):793-801. DOI:10.1046/j.1365-313x.1998.00085.x

1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol(1472-62-4)Related Product Information

• Coclaurine
• (-)-1,2,3,4-Tetrahydro-7,8-dimethoxy-1-[(4-methoxyphenyl)methyl]isoquinoline
• (+)-S-N-Methylcoclaurine Hydrochloride
• GS 389
• N-Methylcoclaurine
• 6,7-Isoquinolinediol, 1,2,3,4-tetrahydro-1-[(4-methoxyphenyl)methyl]-
• Demethyl-Coclaurine
• 1,2,3,4-Tetrahydro-6-methoxy-1-[(4-methoxyphenyl)methyl]-7-isoquinolinol
• 1,2,3,4-Tetrahydro-7-methoxy-1-[(4-methoxyphenyl)methyl]-6-isoquinolinol
• N-nitroso Coclaurine