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LUTEOLIN-4'-O-GLUCOSIDE

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LUTEOLIN-4'-O-GLUCOSIDE Basic information

Product Name:
LUTEOLIN-4'-O-GLUCOSIDE
Synonyms:
  • 4H-1-Benzopyran-4-one, 2-[4-(β-D-glucopyranosyloxy)-3-hydroxyphenyl]-5,7-dihydroxy-
  • 3',4',5,7-TETRAHYDROXYFLAVONE-4'-GLUCOSIDE
  • 2-(4-β-D-Glucopyranosyloxy-3-hydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one
  • 2-[3-Hydroxy-4-(β-D-glucopyranosyloxy)phenyl]-5,7-dihydroxy-4H-1-benzopyran-4-one
  • 3',5,7-Trihydroxy-4'-(β-D-glucopyranosyloxy)flavone
  • 4'-β-D-O-Glucopyranosylluteolin
  • LUTEOLIN-4'-GLUCOSIDE
  • Luteolin-4'-O-glucoside
CAS:
6920-38-3
MF:
C21H20O11
MW:
448.38
Product Categories:
  • Tetra-substituted Flavones
Mol File:
6920-38-3.mol
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LUTEOLIN-4'-O-GLUCOSIDE Chemical Properties

Melting point:
210°C (dec.)
form 
Solid
Boiling point:
814.5±65.0 °C(Predicted)
Density 
1.713±0.06 g/cm3(Predicted)
pka
6.49±0.40(Predicted)
color 
Off-white to yellow
CAS DataBase Reference
6920-38-3(CAS DataBase Reference)
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LUTEOLIN-4'-O-GLUCOSIDE Usage And Synthesis

Uses

Luteolin-4'-O-glucoside is an IL-5 inhibitor with an IC50 of 3.7 μM. Luteolin-4'-O-glucoside resists hyperuricemia and acute gouty arthritis activity. Luteolin-4'-O-glucoside shows anticancer activity[1][2][3].

IC 50

IL-5

References

[1] Park KY, et al. Inhibitory effect of luteolin 4'-O-glucoside from Kummerowia striata and other flavonoids on interleukin-5 bioactivity. Planta Med. 1999 Jun;65(5):457-9. DOI:10.1055/s-2006-960812
[2] Lin Y, et al. Luteolin-4'-O-glucoside and its aglycone, two major flavones of Gnaphalium affine D. Don, resist hyperuricemia and acute gouty arthritis activity in animal models. Phytomedicine. 2018 Mar 1;41:54-61. DOI:10.1016/j.phymed.2018.02.002
[3] Xu T, et al. Glycosylation of luteolin in hydrophilic organic solvents and structure–antioxidant relationships of luteolin glycosides. RSC Advances, 2022, 12(28): 18232-18237.

LUTEOLIN-4'-O-GLUCOSIDESupplier

Meryer (Shanghai) Chemical Technology Co., Ltd.
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