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2-Bromobenzoic acid

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2-Bromobenzoic acid Basic information

Product Name:
2-Bromobenzoic acid
Synonyms:
  • o-bromo-benzoicaci
  • 2-Bromobenzoic aicd
  • 2-bromo-benzoicaci
  • Benzoic acid, o-bromo-
  • benzoicacid,2-bromo-
  • bromobenzoicacid
  • 2-BROMO BENZOIC A
  • 2-Brom-benzoic acid
CAS:
88-65-3
MF:
C7H5BrO2
MW:
201.02
EINECS:
201-848-6
Product Categories:
  • Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
  • Benzoic acid
  • Organic acids
  • Acids & Esters
  • Bromine Compounds
  • C7
  • Aromatic Compounds
  • Carbonyl Compounds
  • Carboxylic Acids
  • alkyl bromide| carboxylic acid
  • bc0001
Mol File:
88-65-3.mol
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2-Bromobenzoic acid Chemical Properties

Melting point:
147-150 °C (lit.)
Boiling point:
86 °C(Press: 4-5 Torr)
Density 
1,929 g/cm3
vapor pressure 
>1 mm Hg ( 20 °C)
refractive index 
1.6080 (estimate)
Flash point:
>100°C
storage temp. 
Sealed in dry,Room Temperature
solubility 
95% ethanol: soluble100mg/mL, clear, colorless to yellow
form 
Powder
pka
2.84(at 25℃)
color 
White to light yellow or beige
Water Solubility 
slightly soluble
BRN 
971266
InChIKey
XRXMNWGCKISMOH-UHFFFAOYSA-N
CAS DataBase Reference
88-65-3(CAS DataBase Reference)
NIST Chemistry Reference
Benzoic acid, 2-bromo-(88-65-3)
EPA Substance Registry System
2-Bromobenzoic acid (88-65-3)
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Safety Information

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-36-37/38-22
Safety Statements 
26-36-24/25-37/39
WGK Germany 
3
RTECS 
DG4448035
Hazard Note 
Irritant
TSCA 
Yes
HS Code 
29163900

MSDS

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2-Bromobenzoic acid Usage And Synthesis

Chemical Properties

White to light yellow crystal powder

Uses

2-Bromobenzoic acid was used in the synthesis of new zinc(II) ? 2-bromobenzoate complex compounds. It was used as the starting reagent in the synthesis of hemilabile benzimidazolyl phosphine ligands.

Synthesis Reference(s)

Canadian Journal of Chemistry, 43, p. 1306, 1965 DOI: 10.1139/v65-178
The Journal of Organic Chemistry, 59, p. 4042, 1994 DOI: 10.1021/jo00094a007

General Description

2-Bromobenzoic acid (2-BA) on condensation with aminoquinolines yields phenylquinolylamines. 2-BA is the common building block for synthesis of various nitrogen heterocycles.

Purification Methods

Crystallise the acid from *C6H6 or MeOH. The anilide has m 141o (from EtOH/H2O). [Beilstein 9 IV 1011.]

2-Bromobenzoic acid Preparation Products And Raw materials

Preparation Products

Raw materials

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