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6-METHOXYLUTEOLIN

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6-METHOXYLUTEOLIN Basic information

Product Name:
6-METHOXYLUTEOLIN
Synonyms:
  • EUPAFOLIN
  • NSC 122416
  • Eupafolin(Nepetin,NSC 122416)
  • Eurafolin
  • Eupafloin 6-Methoxyluteolin
  • 6-METHOXYLUTEOLIN
  • NEPETIN
  • 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-6-methoxy-4H-1-benzopyran-4-one
CAS:
520-11-6
MF:
C16H12O7
MW:
316.26
Product Categories:
  • Tetra-substituted Flavones
Mol File:
520-11-6.mol
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6-METHOXYLUTEOLIN Chemical Properties

Melting point:
267°C
Boiling point:
659.1±55.0 °C(Predicted)
Density 
1.605
Flash point:
90℃
storage temp. 
2-8°C
solubility 
Soluble in methanol;
form 
powder
pka
6.48±0.40(Predicted)
color 
Yellow
Water Solubility 
slightly soluble in water
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6-METHOXYLUTEOLIN Usage And Synthesis

Chemical Properties

Yellow crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from the leaves of Artemisia argyi, the aerial part of the aerial part of A. syringae officinalis.

Uses

Nepetin can be anti-tumor, insecticide, anti-SARS virus, and antibacterial.

Biological Activity

Zelan flavonoid (6-Methoxyluteolin) is a natural flavonoid isolated from Eupatorium ballotaefolium HBK with potent anti-inflammatory activity. Nepetin inhibits IL-6, IL-8 and MCP-1 secretion in ARPE-19 cells with IC50 values of 4.43 μM, 3.42 μM and 4.17 μM, respectively.

target

Calcium Channel | Histamine Receptor

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