2,6-Dimethoxypyridine-3-carboxylic acid Chemical Properties

Melting point:

140-144 °C (lit.)

Boiling point:

293.1±35.0 °C(Predicted)

Density 

1.279±0.06 g/cm3(Predicted)

storage temp. 

Inert atmosphere,Room Temperature

form 

Crystalline Powder

pka

3.63±0.10(Predicted)

color 

White to pale yellow

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-37/39

WGK Germany 

3

HazardClass 

IRRITANT

MSDS

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2,6-Dimethoxypyridine-3-carboxylic acid Usage And Synthesis

Uses

2,6-Dimethoxypyridine-3-carboxylic acid (2,6-dimethoxynicotinic acid, DMPH) may be used in the preparation of novel benzothiazolo naphthyridone carboxylic acid derivatives. It may be used in the preparation of following complexes, via reaction with different precursors [Ti(η⁵-C₅H₅)₂Cl₂], [Ti(η⁵-C₅H₄Me)₂Cl₂], [Ti(η⁵-C₅H₄SiMe₃)(η⁵-C₅H₅)Cl₂], [Ti(η⁵-C₅Me₅)Cl₃], SnMe₃Cl and GatBu₃:

• [Ti(η⁵-C₅H₅)₂(DMP-κO)₂]
• [Ti(η⁵-C₅H₄Me)₂(DMP-κO)₂]
• [Ti(η⁵-C₅H₄SiMe₃)(η⁵-C₅H₅)(DMP-κO)₂
• [Ti(η⁵-C₅Me₅)(DMP-κ²O,O′)₃]
• [SnMe₃(μ-DMP-κO:κO′)]_∞
• [GatBu₂(μ-DMP-κO:κO′)]₂

General Description

2,6-Dimethoxypyridine-3-carboxylic acid (2,6-Dimethoxynicotinic acid, DMNIH) is a piperidine derivative. It forms various organotin(IV) complexes and their antiproliferative action against pancreatic carcinoma (PANC-1), erythroleukemia (K562), and two glioblastoma multiform (U87 and LN-229) human cell lines has been evaluated.

2,6-Dimethoxypyridine-3-carboxylic acid(16727-43-8)Related Product Information

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