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2-METHOXY-3-PYRIDINECARBOXALDEHYDE

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2-METHOXY-3-PYRIDINECARBOXALDEHYDE Basic information

Product Name:
2-METHOXY-3-PYRIDINECARBOXALDEHYDE
Synonyms:
  • 2-METHOXYNICOTINALDEHYDE
  • 2-METHOXY-PYRIDINE-3-CARBALDEHYDE
  • 2-METHOXY-3-PYRIDINECARBOXALDEHYDE
  • 3-Pyridinecarboxaldehyde, 2-methoxy- (9CI)
  • 2-Methoxy-3-pyridinecarboxaldenhyde
  • 2-Methoxy-3-pyridinecaarboxaldehyde
  • 2-METHYOXYNICOTINALDEHYDE
  • 2-Methoxypyridine-3-carboxaldehyde
CAS:
71255-09-9
MF:
C7H7NO2
MW:
137.14
Product Categories:
  • Heterocycle-Pyridine series
  • ALDEHYDE
  • C7 and C8
  • Heterocyclic Building Blocks
  • Pyridines
Mol File:
71255-09-9.mol
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2-METHOXY-3-PYRIDINECARBOXALDEHYDE Chemical Properties

Boiling point:
200-201 °C (lit.)
Density 
1.161 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.5500(lit.)
Flash point:
205 °F
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
form 
Liquid or Low Melting Solid
pka
1.60±0.10(Predicted)
color 
Colorless to yellow
Sensitive 
Air Sensitive
CAS DataBase Reference
71255-09-9(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
41-43-36/37/38
Safety Statements 
26-36/37/39-37
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29339900

MSDS

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2-METHOXY-3-PYRIDINECARBOXALDEHYDE Usage And Synthesis

Chemical Properties

Colorless to yellow liquid

Uses

2-Methoxy-3-pyridinecarboxaldehyde may be used to synthesize the following:

  • ethyl 5-amino-4-(2-methoxy-3-pyridyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrano[2,3-b]quinoline-3-carboxylate, a potent AChE inhibitor
  • N-hydroxy-2-pyridinone-based arylsulfone containing a Zn-binding group (ZBG) as MMP-2/-9 inhibitor

Synthesis Reference(s)

Tetrahedron Letters, 29, p. 773, 1988 DOI: 10.1016/S0040-4039(00)80206-3

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