Triethanolamine borate Chemical Properties

Melting point:

235-237 °C(lit.)

Boiling point:

149.6±39.0 °C(Predicted)

Density 

1.13±0.1 g/cm3(Predicted)

storage temp. 

Room Temperature, under inert atmosphere

solubility 

slightly soluble in acetone, benzene

pka

6.40±0.20(Predicted)

form 

Powder

color 

white

Odor

odorless

BRN 

774536

InChI

InChI=1S/C6H12BNO3/c1-4-9-7-10-5-2-8(1)3-6-11-7/h1-6H2

InChIKey

NKPKVNRBHXOADG-UHFFFAOYSA-N

SMILES

B12OCCN(CCO1)CCO2

CAS DataBase Reference

283-56-7

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36/37

WGK Germany 

3

RTECS 

YJ8968050

F 

10-21

HS Code 

29163990

Toxicity

LD ivn-mus: >100 mg/kg EJMCA5 13,207,78

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

Triethanolamine borate Usage And Synthesis

Chemical Properties

White to off-white solid

Uses

Triethanolamine Borate is an intermediate in the synthesis of Silatrane (S433000) which can be used as a reversible cholinesterase inhibitor. Silatrane and its derivatives can also be used as antitumor agents.

Preparation

triethanolamine borate synthesis: Adding trimethyl borate into the reaction bottle62.7g (0.6mol), 74.6g (0.5mol) of triethanolamine and 300g of toluene are slowly heated to reflux for 1 hour at room temperature, then distillate is distilled out under normal pressure (65-100°C) while reaction is carried out, sampling is carried out by GC detection, after the reaction is finished, reduced pressure concentration is carried out until no liquid distillation is carried out, acetonitrile is added for recrystallization, filtration and drying are carried out, 68g of white solid is obtained, HPLC (high performance liquid chromatography) is 98.8%, and the yield is 86.6%.

General Description

Triethanolamine borate can be formed from the 1:1 aqueous solution of boric acid and triethanolamine. It is used as buffer.

Safety Profile

A poison by intravenous route.When heated to decomposition it emits toxic fumes of NOx.

Triethanolamine borate(283-56-7)Related Product Information

• Monoethanolamine
• TRIETHANOLAMINE HYDROCHLORIDE
• Triethanolamine oleic soap
• Potassium oleate
• Sodium metaborate
• Triisopropyl borate
• Titanium triisostearoylisopropoxide
• Triethyl phosphonoacetate
• TRIETHYL 2-PHOSPHONOPROPIONATE
• TRIETHANOLAMINE PHOSPHATE
• Triethyl phosphate
• Triethyl orthobutyrate
• Glycerol
• Ethylenediaminetetraacetic acid
• Isoquinoline-1-carboxylic acid
• Diethanolamine
• TRIETHYL 2-PHOSPHONOPENTANOATE
• Triethyl acetyl citrate