Homosalate Chemical Properties

Boiling point:

161-165°C (12 torr)

Density 

1.05

vapor pressure 

0.015Pa at 25℃

refractive index 

n20 1.516 to 1.518

Flash point:

169 - 173℃

storage temp. 

Inert atmosphere,Room Temperature

solubility 

Chloroform (Slightly), DMSO (Slightly)

pka

8.10±0.30(Predicted)

form 

Liquid

color 

Colourless

Odor

at 100.00?%. mild menthol

Water Solubility 

<0.1 g/100 mL at 26 ºC

BRN 

2731604

LogP

6.27 at 25℃

CAS DataBase Reference

118-56-9(CAS DataBase Reference)

NIST Chemistry Reference

Homosalate(118-56-9)

EPA Substance Registry System

3,3,5-Trimethylcyclohexyl salicylate (118-56-9)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36/39

WGK Germany 

2

HS Code 

29182300

Homosalate Usage And Synthesis

Description

Homosalate is an organic compound that belongs to a class of chemicals called salicylates. Salicylates prevent direct skin exposure to the sun’s harmful rays by absorbing ultraviolet (UV) light. Homosalate specifically absorbs short-wave UVB rays, associated with DNA damage and an increased risk of skin cancer. It is a widely used chemical in sunscreens and skin care products with SPF. However, Homosalate is a potential endocrine disruptor and studies in cells suggest it may impact hormones. In addition to direct health concerns following homosalate exposure, the chemical may also enhance the absorption of pesticides in the body.

Chemical Properties

Liquid.

Uses

Homosalate used as a UV filter in various personal skin care formulations and cosmetics.

Uses

UV screen, analgesic

Uses

homosalate is a chemical uVB absorber included in the FDA’s Category I Sunscreen Chemical list. Its approved usage level is 4 to 15 percent by the FDA and 10 percent by the european union’s Cosmetic Directive.

Definition

A homolog of menthyl salicylate.

brand name

Eusolex (Rona Laboratories, Great Britain); Heliophan (Greeff).

General Description

Viscous or light yellow to slightly tan liquid or oil.

Air & Water Reactions

Homosalate will hydrolyze under basic conditions. . Insoluble in water.

Reactivity Profile

An ester and a phenol. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.

Fire Hazard

Homosalate is probably combustible.

Flammability and Explosibility

Non flammable

Side effects

Similar to oxybenzone, homosalate affects hormone activity once absorbed. Skin rashes, acne and skin irritation are rare side effects of the toxic chemical. Estrogen, androgen and progesterone have all been found to be disrupted when the body is exposed to homosalate.

Homosalate(118-56-9)Related Product Information

• N,N-Dimethylcyclohexylamine
• Dimethylbenzylcarbinyl acetate
• Sodium salicylate
• 3-Methylsalicylic acid
• Benzyldimethylcarbinyl butyrate
• Cyclohexanol
• 2-Methyl-2-propenoic acid cyclohexyl ester
• Phenyl salicylate
• Isoamyl o-hydroxybenzoate
• Methyl salicylate
• TRILAURIN
• Triisopropyl orthoformate
• ORTHO-N-VALERIC ACID TRIETHYL ESTER
• Triethyl orthoformate
• Tetraethyl orthocarbonate
• Trimethoxymethane
• Triethyl orthoacetate
• ptaquiloside