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4-Hydroxy-L-isoleucine

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4-Hydroxy-L-isoleucine Basic information

Product Name:
4-Hydroxy-L-isoleucine
Synonyms:
  • 4-HYDROXY-L-ISOLEUCINE
  • (2S,3R)-2-aMino-4-hydroxy-3-Methylpentanoic acid
  • L-4- hydroxyl isoleucine
  • (4S)-4-Hydroxy-L-isoleucine from fenugre
  • L-Isoleucine, 4-hydroxy-
  • 4-Hydroxy-L-isoleucine USP/EP/BP
  • 4-Hydroxyisoleucine (1327319)
  • Hydroxy L-isoleucine
CAS:
781658-23-9
MF:
C6H13NO3
MW:
147.17
EINECS:
631-182-5
Product Categories:
  • Amino Acids & Derivatives
  • Aliphatics
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
Mol File:
781658-23-9.mol
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4-Hydroxy-L-isoleucine Chemical Properties

Melting point:
>200°
Boiling point:
332 ºC
Density 
1.181
Flash point:
147 ºC
storage temp. 
2-8°C
pka
2.41±0.25(Predicted)
form 
powder
color 
White
optical activity
[α]/D +34.0±2.0°, c = 1 in H2O
Water Solubility 
Soluble in water
InChIKey
OSCCDBFHNMXNME-UHFFFAOYSA-N
CAS DataBase Reference
781658-23-9(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26
WGK Germany 
3
HS Code 
2922505000
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4-Hydroxy-L-isoleucine Usage And Synthesis

Chemical Properties

4-Hydroxyisoleucine is Light Yellow Solid

Uses

4-Hydroxy-L-isoleucine is used as a treatment for type II diabetes.

Definition

ChEBI: 4-Hydroxy-L-isoleucine is an isoleucine derivative.

Biochem/physiol Actions

A peculiar amino acid extracted from fenugreek seeds and never found in mammalian tissues, exhibits interesting insulinotropic activity; effects on insulin secretion, plant-derived treatment for metabolic syndrome.

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