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D-Alanine

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D-Alanine Basic information

Product Name:
D-Alanine
Synonyms:
  • D-ALANINE, >=98% (HPLC)
  • 291°C (dec)
  • D-Alanine≥ 98% (Titration: Dried basis)
  • D-2-AMINOPROPIONIC ACID
  • D-2-AMINOPROPANOIC ACID
  • D-ALPHA-ALANINE
  • D-ALA
  • D-ALANINE
CAS:
338-69-2
MF:
C3H7NO2
MW:
89.09
EINECS:
206-418-1
Product Categories:
  • Alanine [Ala, A]
  • Amino Acids and Derivatives
  • PROTECTED AMINO ACID & PEPTIDES
  • alpha-Amino Acids
  • Biochemistry
  • Amino Acids and Derivatives
  • Amino Acids Derivatives
  • Amino ACIDS SERIES
  • Amino Acids
  • GABA/Glycine receptor
  • alanine
  • amino acid
  • amino
  • Pyrazoles
  • organic acids
  • pharmaceutical intermediate
  • bc0001
  • Elisa Kit-Mouse Elisa Kit
Mol File:
338-69-2.mol
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D-Alanine Chemical Properties

Melting point:
291 °C (dec.)(lit.)
alpha 
-14.5 º (c=10, 6N HCl)
Boiling point:
212.9±23.0 °C(Predicted)
Density 
1.4310 (estimate)
refractive index 
-14 ° (C=2, 6mol/L HCl)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
H2O: soluble
form 
Crystalline Powder or Crystals
pka
2.31±0.10(Predicted)
color 
White to off-white
Odor
odorless
Water Solubility 
155 g/L (20 ºC)
Merck 
14,204
BRN 
1720249
LogP
-0.574 (est)
CAS DataBase Reference
338-69-2(CAS DataBase Reference)
NIST Chemistry Reference
D-Alanine(338-69-2)
EPA Substance Registry System
D-Alanine (338-69-2)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
24/25-36-26
WGK Germany 
3
TSCA 
Yes
HazardClass 
IRRITANT
HS Code 
29224995

MSDS

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D-Alanine Usage And Synthesis

Chemical Properties

White Crystalline Powder

Uses

D-Alanine is essential for the biosynthesis of peptidoglycan crosslinking sub-units that are used for bacterial cell walls.

Definition

ChEBI: The D-enantiomer of alanine.

Application

D-Alanine is a LHRH-antagonists, e.g., Abarelix (antineoplas- tic)

General Description

Alanine is a non essential amino acid.

Biochem/physiol Actions

D-Alanine is the non-proteinogenic form of alanine which is used in bacterial cell wall biosynthesis. D-Alanine is used to study the specificity and kinetics of alanine racemase(s) (alaR).

Purification Methods

Crystallise alanine from H2O or aqueous EtOH, i.e. crystallise it from 25% EtOH in water, or recrystallise it from 62.5% EtOH, wash it with EtOH and dry it to constant weight in vacuo over P2O5. [Gutter & Kegeles J Am Chem Soc 75 3893 1953, Walsh J Biol Chem 264 2394 1989.] 2,2'-Iminodipropionic acid is a likely impurity. [Beilstein 4 IV 2480. 2481.]

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