(Gly1,Ser3·22,Gln4·34,Thr6,Arg19,Tyr21,Ala23·31,Aib32)-Pancreatic Polypeptide (human)
(Gly1,Ser3·22,Gln4·34,Thr6,Arg19,Tyr21,Ala23·31,Aib32)-Pancreatic Polypeptide (human) Basic information
- Product Name:
- (Gly1,Ser3·22,Gln4·34,Thr6,Arg19,Tyr21,Ala23·31,Aib32)-Pancreatic Polypeptide (human)
- Synonyms:
-
- (Gly1,Ser3·22,Gln4·34,Thr6,Arg19,Tyr21,Ala23·31,Aib32)-Pancreatic Polypeptide (human)
- (Gly1,Gln4·16,Thr6·13,Tyr7,Asp10,Asn11,Pro14,Arg26,Met30,Ala31,Aib32)-Neuropeptide Y (huMan, rat)
- H-Gly-Pro-Ser-Gln-Pro-Thr-Tyr-Pro-Gly-Asp-Asn-Ala-Thr-Pro-Glu-Gln-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-Arg-Tyr-Ile-Asn-Met-Ala-Aib-Arg-Gln-Arg-Tyr-NH2
- PubChem ID: 90479787
- (Gly1,Ser3middot22,Gln4middot34,Thr6,Arg19,Tyr21,Ala23middot31,Aib32)-Pancreatic Polypeptide (human)
- Glycyl-L-prolyl-L-seryl-L-glutaminyl-L-prolyl-L-threonyl-L-tyrosyl-L-prolylglycyl-L-α-aspartyl-L-asparaginyl-L-alanyl-L-threonyl-L-prolyl-L-α-glutamyl-L-glutaminyl-L-methionyl-L-alanyl-L-arginyl-L-tyrosyl-L-tyrosyl-L-seryl-L-alanyl-L-leucyl-L-arginyl-L-arginyl-L-tyrosyl-L-isoleucyl-L-asparaginyl-L-methionyl-L-alanyl-2-methylalanyl-L-arginyl-L-glutaminyl-L-arginyl-L-tyrosinamide
- (Gly?,Ser?·??,Gln?·??,Thr?,Arg??,Tyr??,Ala??·??,Aib??)-Pancreatic Polypeptide (human) trifluoroacetate salt
- Gly1,Gln4·16,Thr6·13,Tyr7,Asp10,Asn11,Pro14,Arg26
- CAS:
- 313988-89-5
- MF:
- C183H281N57O54S2
- MW:
- 4207.66874
- Mol File:
- 313988-89-5.mol
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(Gly1,Ser3·22,Gln4·34,Thr6,Arg19,Tyr21,Ala23·31,Aib32)-Pancreatic Polypeptide (human) Chemical Properties
- storage temp.
- Store at -20°C
- solubility
- Soluble to 1 mg/ml in 10% acetonitrile
- form
- Powder
- color
- White to off-white
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(Gly1,Ser3·22,Gln4·34,Thr6,Arg19,Tyr21,Ala23·31,Aib32)-Pancreatic Polypeptide (human) Usage And Synthesis
Biological Activity
cPP1-7,NPY19-23,Ala31,Aib32,Gln34 is a potent and selective neuropeptide YY5 receptor agonist with IC50 of 0.24 nM for hY5 receptor binding. It increases dietary intake.
in vitro
cPP1-7,NPY19-23,Ala31,Aib32,Gln34 has IC 50 s of 530 nM, >500 nM , 51 nM for binding to the hY 1 , hY 4 , hY 2 receptors.
in vivo
cPP1-7,NPY19-23,Ala31,Aib32,Gln34 induces a high amount of food intake in a dose-dependent manner in adult male rats weighing 340-400 g.
target
| hY 5 receptor < /p> 0.24 nM (IC 50 ) | hY 1 receptor 530 nM (IC 50 ) | hY 2 receptor >500 nM (IC 50 ) | hY 4 receptor 51 nM (IC 50 ) |
(Gly1,Ser3·22,Gln4·34,Thr6,Arg19,Tyr21,Ala23·31,Aib32)-Pancreatic Polypeptide (human)Supplier
GL Biochem (Shanghai) Ltd
- Tel
- 21-61263452 13641803416
- ymbetter@glbiochem.com
Chemsky (shanghai) International Co.,Ltd
- Tel
- 021-50135380
- shchemsky@sina.com
Nanjing Leon Biological Technology Co., Ltd.
- Tel
- 17705183659
- sales@njleonbiotech.com
Nanjing Peptide Biotech Ltd.
- Tel
- 025-025-58361106-805-805 13082558573
- liugang@njpeptide.com
Chengdu Youngshe Chemical Co., Ltd.
- Tel
- +86-17380623303 +86-17380623303
- Caroline@youngshechem.com
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(Gly1,Ser3·22,Gln4·34,Thr6,Arg19,Tyr21,Ala23·31,Aib32)-Pancreatic Polypeptide (human)(313988-89-5)Related Product Information
- TCS 184
- D-Trp(34) neuropeptide Y
- AC-LEU-ASP-GLN-TRP-PHE-GLY-NH2
- PTH (1-84) (HUMAN)
- Compstatin control peptide
- ECHISTATIN
- GATX2
- APETx2
- ω-Agatoxin TK
- Cyclo[L-α-aspartyl-D-phenylalanyl-L-lysyl-N5-[[[(2,3-dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-L-ornithylglycyl], 1,1-dimethylethyl ester
- MM 54
- Vosoritide acetate
- PDZ1 DOMAIN INHIBITOR PEPTIDE