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1-N-Boc-4-(Phenylamino)piperidine

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1-N-Boc-4-(Phenylamino)piperidine Basic information

Product Name:
1-N-Boc-4-(Phenylamino)piperidine
Synonyms:
  • TERT-BUTYL 4-ANILINOTETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE
  • 4-(Phenylamino)piperidine, N1-BOC protected
  • 1-N-BOC-4-(PHENYLAMINO)PIPERIDINE
  • tert-butyl 4-anilinotetrahydro-1(2H)-pyridinecarboxylate (en)
  • N-tert-Butoxycarbonyl-4-anilinopiperidine
  • 1-N-Boc-4-(Pheny 1-N-Boc-4-(Phenylamino)piperidinelamino)piperidine
  • 1-N-Boc-4-(Phenylamino)piperidine Supplier
  • 1-N-Boc-4-(Phenylamino)
CAS:
125541-22-2
MF:
C16H24N2O2
MW:
276.37
EINECS:
203-105-0
Product Categories:
  • Intermediates
  • inter
  • Aromatics
  • Heterocycles
  • pharmaceutical
  • Intermediate
  • 125541-22-2
  • Pharm
Mol File:
125541-22-2.mol
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1-N-Boc-4-(Phenylamino)piperidine Chemical Properties

Melting point:
136-137
Boiling point:
400.6±38.0 °C(Predicted)
Density 
1.107±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
DMF: 15mg/mL; DMSO: 25mg/mL; Ethanol: 25mg/mL; Ethanol:PBS (pH 7.2) (1:1): 0.5mg/mL
form 
A crystalline solid
pka
5.00±0.20(Predicted)
InChI
InChI=1S/C16H24N2O2/c1-16(2,3)20-15(19)18-11-9-14(10-12-18)17-13-7-5-4-6-8-13/h4-8,14,17H,9-12H2,1-3H3
InChIKey
HTIWISWAPVQGMI-UHFFFAOYSA-N
SMILES
N1(C(OC(C)(C)C)=O)CCC(NC2=CC=CC=C2)CC1
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Safety Information

Hazard Codes 
Xi,Xn
Risk Statements 
22
Hazard Note 
Harmful/Irritant
HazardClass 
IRRITANT
HS Code 
2933399990
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1-N-Boc-4-(Phenylamino)piperidine Usage And Synthesis

Description

4-Anilino-1-Boc-piperidine is an analytical reference standard that is structurally similar to known opioids. 4-Anilino-1-Boc-piperidine is a precursor in the synthesis of 4-anilinopiperidine . This product is intended for research and forensic applications.

Chemical Properties

Pale Brown Solid

Uses

Intermediate in the preparation of Fentanyl derivatives.

Application

1-N-Boc-4-(Phenylamino)piperidine is an amino acid derivative widely employed as a reagent in organic synthesis. This compound exhibits remarkable versatility, finding applications in various fields such as peptide and protein synthesis, organic synthesis, and drug development. It possesses strong basic properties, allowing for diverse reactions with acids that lead to the formation of a wide array of products. The extensive use of this compound in organic synthesis is well-documented, particularly in the synthesis of peptides and proteins. By facilitating the coupling of amino acids, it enables the creation of peptides that can be utilized in diverse applications, including the development of pharmaceutical drugs.

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1-N-Boc-4-(Phenylamino)piperidine(125541-22-2)Related Product Information