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Quinoline, 6,7-dimethoxy-4-(4-nitrophenoxy)-

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Quinoline, 6,7-dimethoxy-4-(4-nitrophenoxy)- Basic information

Product Name:
Quinoline, 6,7-dimethoxy-4-(4-nitrophenoxy)-
Synonyms:
  • Quinoline, 6,7-dimethoxy-4-(4-nitrophenoxy)-
  • 6,7-dimethoxy-4-(4-nitrophenoxy)-Quinoline
  • Cabozantinib Genotoxic Impurity II
  • 6,7-dimethoxy-4-(4-nitrophenoxy)quinolineQ: What is 6,7-dimethoxy-4-(4-nitrophenoxy)quinoline Q: What is the CAS Number of 6,7-dimethoxy-4-(4-nitrophenoxy)quinoline
  • Cabozantinib Nitro Analog
  • 6,7-dimethoxy-4-(4-nitrophenoxy)quinoline? (Cabozantinib Impurity)
CAS:
190728-24-6
MF:
C17H14N2O5
MW:
326.3
Mol File:
190728-24-6.mol
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Quinoline, 6,7-dimethoxy-4-(4-nitrophenoxy)- Chemical Properties

Boiling point:
480.9±40.0 °C(Predicted)
Density 
1.319±0.06 g/cm3(Predicted)
pka
4.33±0.30(Predicted)
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Quinoline, 6,7-dimethoxy-4-(4-nitrophenoxy)- Usage And Synthesis

Uses

6,7-Dimethoxy-4-(4-nitrophenoxy)quinoline is a related compound of cabozantinib (CAS# 849217-68-1) with potential anticancer activity. It can be used in the preparation of nicotinamide derivatives as Aurora kinase inhibitors, nquinolinyloxyphenylbenzenesulfonamides as AXL kinase inhibitors, N-phenyl-N'-{4-(4-quinolyloxy)phenyl}ureas as vascular endothelial growth factor receptor 2 (VEGFR-2) tyrosine kinase inhibitors, and phenoxyquinolines as specific inhibitors of platelet-derived growth factor receptor tyrosine kinase.

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