Quinoline, 6,7-dimethoxy-4-(4-nitrophenoxy)- Chemical Properties

Boiling point:

480.9±40.0 °C(Predicted)

Density 

1.319±0.06 g/cm3(Predicted)

pka

4.33±0.30(Predicted)

InChI

InChI=1S/C17H14N2O5/c1-22-16-9-13-14(10-17(16)23-2)18-8-7-15(13)24-12-5-3-11(4-6-12)19(20)21/h3-10H,1-2H3

InChIKey

YRYKZXCOGVCXBN-UHFFFAOYSA-N

SMILES

N1C2C(=CC(OC)=C(OC)C=2)C(OC2=CC=C([N+]([O-])=O)C=C2)=CC=1

Quinoline, 6,7-dimethoxy-4-(4-nitrophenoxy)- Usage And Synthesis

Uses

6,7-Dimethoxy-4-(4-nitrophenoxy)quinoline is a related compound of cabozantinib (CAS# 849217-68-1) with potential anticancer activity. It can be used in the preparation of nicotinamide derivatives as Aurora kinase inhibitors, nquinolinyloxyphenylbenzenesulfonamides as AXL kinase inhibitors, N-phenyl-N'-{4-(4-quinolyloxy)phenyl}ureas as vascular endothelial growth factor receptor 2 (VEGFR-2) tyrosine kinase inhibitors, and phenoxyquinolines as specific inhibitors of platelet-derived growth factor receptor tyrosine kinase.

Quinoline, 6,7-dimethoxy-4-(4-nitrophenoxy)-(190728-24-6)Related Product Information

• 4-Aminoveratrole
• Cabozantinib Impurity 5
• N-(4-fluorophenyl)-N-(4-hydroxyphenyl)cyclopropane-1,1-dicarboxamide
• 4-chloro-6,7-dimethoxyquinoline
• Cabozantinib Impurity EXA
• Cabozantinib impurity DX2
• 1-(4-Fluorophenylcarbamoyl)cyclopropanecarboxylic acid
• Cyclopropanecarboxylic acid, 1-[[[4-[[7-methoxy-6-(sulfooxy)-4-quinolinyl]oxy]phenyl]amino]carbonyl]-
• 1,1-Cyclopropanedicarboxamide,N-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N'-phenyl-
• Cyclopropanecarboxylic acid, 1-[(phenylaMino)carbonyl]-
• Cabozantinib Malate
• 1,1-Cyclopropanedicarboxamide, N,N'-bis[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-
• Cabozantinib impurity 1DYH
• Cyclopropanecarboxylic acid, 1-[[(2-fluorophenyl)amino]carbonyl]-