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PEG6-Tos

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PEG6-Tos Basic information

Product Name:
PEG6-Tos
Synonyms:
  • 14-Hydroxy-3,6,9,12-tetraoxatetradecyl 4-methylbenzenesulfonate
  • PEG6-Tos
  • Tos-PEG5-OH
  • OH-PEG5-Tos
  • 3,6,9,12-Tetraoxatetradecane-1,14-diol, 1-4-methylbenzenesulfonate
  • Hydroxy-PEG6-Tos
  • Toluene-4-sulfonic acid 2-(2-{2-[2-(2-hydroxyethoxy)-ethoxy]-ethoxy}-ethoxy)-ethyl ester
  • HO-(CH2CH2O)5-Tos
CAS:
155130-15-7
MF:
C17H28O8S
MW:
392.46
Product Categories:
  • peg
Mol File:
155130-15-7.mol
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PEG6-Tos Chemical Properties

Boiling point:
524.4±50.0 °C(Predicted)
Density 
1.206±0.06 g/cm3(Predicted)
solubility 
DMSO: 100 mg/mL (254.80 mM)
solubility 
DMSO: 100 mg/mL (254.80 mM)
pka
14.36±0.10(Predicted)
Water Solubility 
Water: 100 mg/mL (254.80 mM)
Water Solubility 
Water: 100 mg/mL (254.80 mM)
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PEG6-Tos Usage And Synthesis

Description

PEG6-Tos is a PEG linker containing a hydroxyl group with a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The tosyl group is a very good leaving group for nucleophilic substitution reactions.

Uses

Pentaethylene Glycol Monotosylate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

PEG6-TosSupplier

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