3-Bromo-2-chloro-5-nitropyridine Chemical Properties

Melting point:

54-58

Boiling point:

293.8±35.0 °C(Predicted)

Density 

1.936±0.06 g/cm3(Predicted)

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

form 

powder to crystal

pka

-4.99±0.10(Predicted)

color 

Light yellow to Brown to Dark green

InChIKey

PTTQIUHVDDBART-UHFFFAOYSA-N

CAS DataBase Reference

5470-17-7(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi,T

Risk Statements 

25-41

Safety Statements 

26-39-45

RIDADR 

2811

WGK Germany 

1

HazardClass 

IRRITANT

PackingGroup 

Ⅲ

HS Code 

2933399990

3-Bromo-2-chloro-5-nitropyridine Usage And Synthesis

Uses

3-Bromo-2-chloro-5-nitropyridine is a raw material for the preparation of other organic substances and can be used as a reagent or intermediate component in organic synthesis.

Synthesis

3-Bromo-2-chloro-5-nitropyridine is synthesised using 3-Bromo-2-hydroxy-5-nitropyridine as raw material by chemical reaction. The specific synthesis steps are as follows:
Second step POCI3 (3 ml) was added at 0°C to the mixture of 3-Bromo-2-hydroxy-5-nitropyridine (7.25 g, 33 mmol) and quinoline (2 ml, 16.5 mmol). This reaction medium was heated at 12000 for 2.5 hours and then, after cooling to room temperature, 20 ml of water were added. The precipitate formed was collected by filtration and dried to give the expected 3-Bromo-2-chloro-5-nitropyridine in the form of a brown solid, in a yield of 95percent (7.5 g).The NMR analyses (1H 400 MHz DMSO-d6) are in accordance with the expected structure.

3-Bromo-2-chloro-5-nitropyridine(5470-17-7)Related Product Information

• 2-Chloro-3-nitropyridine
• 2-Chloro-5-chloromethylpyridine
• 2-Chloro-5-nitropyridine
• Clopidol
• 1-Chloro-3-nitrobenzene
• 2-Chloro-3-cyanopyridine
• 3-Bromo-2-chloropyridine
• 1-Hexadecylpyridinium bromide
• 2-Bromo-5-nitropyridine
• 2-Chloro-3-bromo-5-methylpyridine
• 3-BROMO-2-CHLORO-6-PICOLINE
• 5-Chloro-2-bromo-3-nitropyridine
• 2-Nitrochlorobenzene
• Difluorochloromethane
• 3-Amino-5-bromopyridine
• 3-Bromonitrobenzene
• 2-CHLORO-5-BROMO-3-NITROPYRIDINE
• Bromine