GOSSYPIN
GOSSYPIN Basic information
- Product Name:
- GOSSYPIN
- Synonyms:
-
- 3,3',4',5,7,8-HEXAHYDROXYFLAVONE 8-GLUCOSIDE
- 3,3',4',5,7-PENTAHYDROXY-8-O-GLUCOSYLFLAVONE
- GOSSYPIN
- ,7-trihydroxy-
- 2-(3,4-dihydroxyphenyl)-8-(beta-d-glucopyranosyloxy)-3,5,7-trihydroxy-4h-1-b
- 4h-1-benzopyran-4-one,2-(3,4-dihydroxyphenyl)-8-(beta-d-glucopyranosyloxy)-3,5
- gossypin from hibiscus vitifolius*flowers
- COTTON CELLULOSE
- CAS:
- 652-78-8
- MF:
- C21H20O13
- MW:
- 480.38
- Product Categories:
-
- Flavanols
- Mol File:
- 652-78-8.mol
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GOSSYPIN Chemical Properties
- Melting point:
- 229-230°C
- Boiling point:
- 886.0±65.0 °C(Predicted)
- Density
- 1.883±0.06 g/cm3 (20 ºC 760 Torr)
- storage temp.
- -20°C
- solubility
- DMSO: soluble15mg/mL, clear
- form
- powder
- pka
- 5.70±0.40(Predicted)
- color
- light yellow to dark green-yellow
- LogP
- -1.320 (est)
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Safety Information
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-62-37/38-36-22
- Safety Statements
- 26-36-37
- WGK Germany
- 3
- RTECS
- DJ3009900
- HS Code
- 2938909090
MSDS
- Language:English Provider:SigmaAldrich
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GOSSYPIN Usage And Synthesis
Uses
antiinflammatory, antiangiogenesis, antineoplastic, inhibits NF-kB cell response
Definition
ChEBI: A glycosyloxyflavone that is gossypetin attached to a beta-D-glucopyranosyl residue at position 8 via a glycosidic linkage.
Biological Activity
Gossypin is an anti-inflammatory pentahydroxyflavone glucoside isolated from Hibiscus vitifolius th at is used as an herbal remedy for diabetes, jaundice, and inflammation. Gossypin potently inhibits human cancer cell proliferation, including melanoma and glioma cells. Gossypin directly binds and inhibits BRAFV600E and CDK4 kinases, and also regulates Chk1 and Cdc25C in U251 glioma cells.
GOSSYPINSupplier
Z-trans Biochemistry Technology (Suzhou) Co.,Ltd Gold
- Tel
- 0512-66317708 13372112871
- huijuan@zitrans.cn
Meryer (Shanghai) Chemical Technology Co., Ltd.
- Tel
- 021-61259108 18621169109
- market03@meryer.com
Capot Chemical Co., Ltd
- Tel
- +86 (0) 571 85 58 67 18
- sales@capotchem.com
Shanghai TaoSu Biochemical Technology Co., Ltd.
- Tel
- 021-33632979
- info@tsbiochem.com
Sichuan Wei Keqi Biological Technology Co., Ltd.
- Tel
- 028-81700200 18116577057
- 3003855609@qq.com
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GOSSYPIN(652-78-8)Related Product Information
- 3',4',7,8-TETRAHYDROXYFLAVONE
- 2',5'-Dihydroxyacetophenone
- 2',3',4'-TRIHYDROXYACETOPHENONE
- 2'-Hydroxy-5'-methoxyacetophenone
- GOSSYPIN
- Ethyl vanillin
- Homovanillyl alcohol
- 4-Butoxyphenol
- Wogonin
- Eugenol
- 3-(METHOXYMETHOXY)BENZALDEHYDE
- 3-Ethoxyacetophenone
- 3-(2-HYDROXYETHOXY)BENZALDEHYDE
- 2-Propoxyphenol
- Quercetin
- 2',3'-DIMETHOXYACETOPHENONE
- 2-(2-Methoxyphenoxy)ethanol
- AKOS B000301