Basic information Safety Supplier Related

GOSSYPIN

Basic information Safety Supplier Related

GOSSYPIN Basic information

Product Name:
GOSSYPIN
Synonyms:
  • 3,3',4',5,7,8-HEXAHYDROXYFLAVONE 8-GLUCOSIDE
  • 3,3',4',5,7-PENTAHYDROXY-8-O-GLUCOSYLFLAVONE
  • GOSSYPIN
  • ,7-trihydroxy-
  • 2-(3,4-dihydroxyphenyl)-8-(beta-d-glucopyranosyloxy)-3,5,7-trihydroxy-4h-1-b
  • 4h-1-benzopyran-4-one,2-(3,4-dihydroxyphenyl)-8-(beta-d-glucopyranosyloxy)-3,5
  • gossypin from hibiscus vitifolius*flowers
  • COTTON CELLULOSE
CAS:
652-78-8
MF:
C21H20O13
MW:
480.38
Product Categories:
  • Flavanols
Mol File:
652-78-8.mol
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GOSSYPIN Chemical Properties

Melting point:
229-230°C
Boiling point:
886.0±65.0 °C(Predicted)
Density 
1.883±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. 
-20°C
solubility 
DMSO: soluble15mg/mL, clear
form 
powder
pka
5.70±0.40(Predicted)
color 
light yellow to dark green-yellow
LogP
-1.320 (est)
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Safety Information

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-62-37/38-36-22
Safety Statements 
26-36-37
WGK Germany 
3
RTECS 
DJ3009900
HS Code 
2938909090

MSDS

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GOSSYPIN Usage And Synthesis

Uses

antiinflammatory, antiangiogenesis, antineoplastic, inhibits NF-kB cell response

Definition

ChEBI: A glycosyloxyflavone that is gossypetin attached to a beta-D-glucopyranosyl residue at position 8 via a glycosidic linkage.

Biological Activity

Gossypin is an anti-inflammatory pentahydroxyflavone glucoside isolated from Hibiscus vitifolius th at is used as an herbal remedy for diabetes, jaundice, and inflammation. Gossypin potently inhibits human cancer cell proliferation, including melanoma and glioma cells. Gossypin directly binds and inhibits BRAFV600E and CDK4 kinases, and also regulates Chk1 and Cdc25C in U251 glioma cells.

GOSSYPIN Preparation Products And Raw materials

Preparation Products

GOSSYPINSupplier

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