Wogonin Chemical Properties

Melting point:

203-206°C

Boiling point:

518.8±50.0 °C(Predicted)

Density 

1.420±0.06 g/cm3(Predicted)

storage temp. 

Inert atmosphere,2-8°C

solubility 

DMSO: ≥20mg/mL

pka

6.83±0.40(Predicted)

form 

Yellow solid

color 

Light Yellow to Yellow

λmax

319nm(EtOH)(lit.)

InChIKey

XLTFNNCXVBYBSX-UHFFFAOYSA-N

LogP

2.140 (est)

CAS DataBase Reference

632-85-9(CAS DataBase Reference)

Safety Information

Safety Statements 

24/25

WGK Germany 

3

RTECS 

LK8331000

HS Code 

29329990

Wogonin Usage And Synthesis

Appearance

Yellow solid powder

Uses

Wogonin acts as an anti-inflammatory agent, attenuating ovalbumin antigen-influenced neutrophillic airway inflammation. In addition, it reverses multi-drug resistance of human myelogenous leukemia.

Definition

ChEBI: A dihydroxy- and monomethoxy-flavone in which the hydroxy groups are positioned at C-5 and C-7 and the methoxy group is at C-8.

General Description

Wogonin is a flavonoid component of Scutellaria baicalensis Georgi roots.

Biochem/physiol Actions

Wogonin is an anti-inflammatory agent and COX-2 inhibitor, which inhibits the induction of both iNOS and COX-2. Wogonin inhibits COX-2 (IC50 = 46 μM) without affecting COX-1. Wogonin inhibits iNOS induction and thus inhibts activation-induced C6 glial cell death. Specifically, Wogonin inhibits NF-kappaB-mediated iNOS induction.

storage

Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). 

Wogonin(632-85-9)Related Product Information

• p-Anisaldehyde
• Baicalin
• 4-Methoxybenzylchloride
• 4-Methoxyphenylacetone
• Anisole
• 3-Methoxybenzaldehyde
• (Trifluoromethoxy)benzene
• SCUTELLAREIN
• p-Anisidine
• PHENYL VALERATE
• Wogonin-7β-glucuronide,Wogonin 7-O-glucuronide
• Taxifolin
• Kidney Bean Extract
• WEDELOLACTONE
• WILFORINE
• Worenine
• WILFORDINE
• HYPERICUM PERFORATUM OIL