3',4',7,8-TETRAHYDROXYFLAVONE Chemical Properties

Melting point:

309～310℃

Boiling point:

618.9±55.0 °C(Predicted)

Density 

1.654±0.06 g/cm3(Predicted)

storage temp. 

Amber Vial, Refrigerator, Under inert atmosphere

solubility 

Methanol (Slightly, Heated)

pka

6.86±0.40(Predicted)

form 

Solid

color 

Light Yellow

Stability:

Light Sensitive

LogP

2.030 (est)

3',4',7,8-TETRAHYDROXYFLAVONE Usage And Synthesis

Uses

7,8,3′,4′-Tetrahydroxyflavone (compound 2) is a potent xanthine oxidase (XOD) inhibitor with an IC50 value of 10.488 μM[1].

Definition

ChEBI: 2-(3,4-dihydroxyphenyl)-7,8-dihydroxy-1-benzopyran-4-one is a member of flavones. It is a conjugate acid of a 3',4',8-trihydroxyflavone-7-olate.

References

[1] Tung YT, et al. Inhibition of xanthine oxidase by Acacia confusa extracts and their phytochemicals. J Agric Food Chem. 2010 Jan 27;58(2):781-6. DOI:10.1021/jf901498q

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