Safety Information

Hazard Codes 

T

Risk Statements 

23/24/25

Safety Statements 

36/37/39-45

RIDADR 

3172

HazardClass 

6.1(a)

PackingGroup 

I

ATRACTYLOSIDE SODIUM SALT Usage And Synthesis

Chemical Properties

ATRACTYLOSIDE SODIUM SALT is White Solid

Uses

A specific inhibitor of the adenine nucleotide translocase (ANT), which is a mitochondrial ADP/ATP carrier. It is also a proapoptotic ligand of ANT that induces pore formation by ANT, and results in p ermeabilization of the mitochondria membrane. Studies on rat hearts suggest that Atractyloside inhibits chloride channels from the mitochondrial membrane. It is used to probe the source of procaspase 8 in human fibroblasts and mouse clonal striatal cells, as related to death receptor-mediated apoptosis. ATRACTYLOSIDE SODIUM SALT induces the release of ahyaluronidase-induced murine WW domain-containing oxidore ductase from cultured COS-7 cells, with respect to tumor necrosis factor cytotoxicity.

ATRACTYLOSIDE SODIUM SALT(100938-11-2)Related Product Information

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