Basic information Safety Supplier Related

6-Methoxyindole

Basic information Safety Supplier Related

6-Methoxyindole Basic information

Product Name:
6-Methoxyindole
Synonyms:
  • 6-Methoxyindole, 98% 500MG
  • 6-methoxy-1H-indole(SALTDATA: FREE)
  • 6-Methoxy-1H-indole 98%
  • 6-(Methyloxy)-1H-indole
  • NSC 92517
  • Indole, 6-methoxy-
  • 1H-Indole, 6-methoxy-
  • 1H-INDOL-6-YL METHYL ETHER
CAS:
3189-13-7
MF:
C9H9NO
MW:
147.17
EINECS:
221-689-6
Product Categories:
  • Indole
  • Pyrroles & Indoles
  • Indole and Indoline
  • Simple Indoles
  • Building Blocks
  • Heterocyclic Building Blocks
  • blocks
  • IndolesOxindoles
  • Indole/indoline/oxindole
  • pharmacetical
  • Pyrroles & Indoles
  • Indoles
  • Indole Series
  • Indole Derivatives
  • Heterocycle-Indole series
  • bc0001
Mol File:
3189-13-7.mol
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6-Methoxyindole Chemical Properties

Melting point:
90-92 °C (lit.)
Boiling point:
105°C 0,2mm
Density 
1.169±0.06 g/cm3(Predicted)
Flash point:
105°C/0.2mm
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Methanol (Slightly)
pka
17.22±0.30(Predicted)
form 
Shiny Crystals
color 
White
Sensitive 
Light Sensitive
BRN 
116483
InChIKey
QJRWYBIKLXNYLF-UHFFFAOYSA-N
CAS DataBase Reference
3189-13-7(CAS DataBase Reference)
NIST Chemistry Reference
Indole, 6-methoxy-(3189-13-7)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
Hazard Note 
Irritant/Keep Cold
HazardClass 
IRRITANT, LIGHT SENSITIVE
HS Code 
29339900

MSDS

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6-Methoxyindole Usage And Synthesis

Chemical Properties

white shiny crystals

Uses

6-Methoxyindole was used to study the fluorescence of protonated excited-state forms of serotonin and other related compounds in acid. It was used in the preparation of:

  • tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles, potential anticancer immunomodulator
  • indolylindazoles and indolylpyrazolopyridines, interleukin-2 inducible T cell kinase inhibitors
  • diindolyloxyindoles, anticancer agents
  • benzoylpiperazinyl-indolyl ethane dione derivatives, HIV-1 inhibitors
  • 3-aroylindoles as anticancer agents
  • indolyl and isoquinolinyl anthranilates, PPARδ partial agonists
  • heteroaryl ketones, VEGFR-2 inhibitors

Synthesis Reference(s)

Synthesis, p. 735, 1986 DOI: 10.1055/s-1986-31759

Biochem/physiol Actions

6-Methoxyindole inhibits the chlorinating activity of myeloperoxidase and inhibits the generation of hypochlorous acid released by activated leukocytes.

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