cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl-4-methylbenzenesulphonate
cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl-4-methylbenzenesulphonate Basic information
- Product Name:
- cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl-4-methylbenzenesulphonate
- Synonyms:
-
- cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl-4-methylbenzenesulphonate
- CIS-2-(2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOLE-1-YL)METHYL-4-(P-TOLUENE SULFONYLOXY) METHYL-1,3-DIOXALANE
- CIS-[2-(2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOL-YL METHYL)-1,3-DIOXOLANE-4-YL]-P-METHYLBENZENE SULFONATE
- CIS-TOSYLATE
- ACTIVITY ESTEROF KETOCONAZOL
- CIS-[2-(2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOL-YL METHYL)-1,3-DIOXOLANE-4-YL]-P-METHYLBENZENE SULFONATE OR -P-METHYL SULFONATE (KETOCONAZLE INTERMEDIATE)
- Ketoconazole EP Impurity E
- Cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-l-ylmethyl)- 1,3-dioxolan-4-yl]methyl-4-methylbenzenesulphonate (CisTosylate)
- CAS:
- 134071-44-6
- MF:
- C21H20Cl2N2O5S
- MW:
- 483.36
- EINECS:
- 603-791-6
- Product Categories:
-
- Aromatics
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Heterocycles
- Intermediates
- Sulfur & Selenium Compounds
- Pharmaceutical Intermediates
- Mol File:
- 134071-44-6.mol
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cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl-4-methylbenzenesulphonate Chemical Properties
- Melting point:
- 120-122°C
- Boiling point:
- 665.7±55.0 °C(Predicted)
- Density
- 1.44±0.1 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 6.88±0.12(Predicted)
- color
- White to Off-White
- InChI
- InChI=1/C21H20Cl2N2O5S/c1-15-2-5-18(6-3-15)31(26,27)29-12-17-11-28-21(30-17,13-25-9-8-24-14-25)19-7-4-16(22)10-20(19)23/h2-10,14,17H,11-13H2,1H3/t17-,21-/s3
- InChIKey
- WAXNIYHZFWRPGS-NTMXNBFVNA-N
- SMILES
- [C@@]1(OC[C@@H](COS(=O)(=O)C2C=CC(C)=CC=2)O1)(CN1C=NC=C1)C1=CC=C(Cl)C=C1Cl |&1:0,3,r|
- CAS DataBase Reference
- 134071-44-6(CAS DataBase Reference)
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cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl-4-methylbenzenesulphonate Usage And Synthesis
Chemical Properties
Off-White Solid
Uses
cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl p-Tolylsulfonate (Ketoconazole EP Impurity E) is an intermediate in the synthesis of the drug Ketoconazole (K186000).
cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl-4-methylbenzenesulphonateSupplier
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cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl-4-methylbenzenesulphonate(134071-44-6)Related Product Information
- Mebendazole
- Imidazole
- Dichlorodiphenylsilane
- Dichloromethylphenylsilane
- Phenylphosphonic dichloride
- Ketoconazole
- Ketoconazole Impurity 1
- Ketoconazole Impurity 4
- Ketoconazole Impurity 9 (Ketoconazole Hydroxymethyl Impurity)
- Ketoconazole Impurity 6
- Ketoconazole Impurity 15
- KETOCONAZOLE INTERMEDIATE
- cis-1-[4-[[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine
- 2,3-Dehydro Ketoconazole
- N-Acetylpiperazine-N'-(4-phenol) Ketoconazole
- rac-trans-Ketoconazole
- Ketoconazole Impurity 2
- KetoconazoleN-Oxide