Basic information Safety Supplier Related

KETOCONAZOLE INTERMEDIATE

Basic information Safety Supplier Related

KETOCONAZOLE INTERMEDIATE Basic information

Product Name:
KETOCONAZOLE INTERMEDIATE
Synonyms:
  • KETOCONAZOLE INTERMEDIATE
  • cis-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolane-4-methanol
  • [(R)-2-(2,4-DICHLORO-PHENYL)-2-IMIDAZOL-1-YLMETHYL-[1,3]DIOXOLAN-4-YL]-METHANOL
  • CIS-2-(2,4-DICHLOROPHENYL)-2- (1H-IMIDAZOL-1-YLMETHYL)-1,3
  • rel-2α*-(1H-Imidazole-1-ylmethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolane-4α*-methanol
  • (2R,4S)-rel-2-(2,4-dichlorophenyl)-2-(1H-iMidazol-1-ylMethyl)-1,3-dioxolane-4-Methanol
  • rac-Ketoconazole Hydroxymethyl Impurity
  • Ketoconazole Impurity 8
CAS:
61397-58-8
MF:
C14H14Cl2N2O3
MW:
329.18
EINECS:
262-766-4
Product Categories:
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
Mol File:
61397-58-8.mol
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KETOCONAZOLE INTERMEDIATE Chemical Properties

Melting point:
99-101 °C
Boiling point:
529.1±50.0 °C(Predicted)
Density 
1.48±0.1 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
14.20±0.10(Predicted)
color 
White
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KETOCONAZOLE INTERMEDIATE Usage And Synthesis

Chemical Properties

White Solid

Uses

cis-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolane-4-methanol is a Ketoconazole (K186000) fragment that may have modulatory activity on the large conductance calcium-activated potassium channel (BKCa).

KETOCONAZOLE INTERMEDIATESupplier

BTC Pharmaceutical CO. Ltd Gold
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Chemsky(shanghai)International Co.,Ltd.
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Hangzhou Sage Chemical Co., Ltd.
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