4-(1-Acetylpiperazin-4-yl)phenol
4-(1-Acetylpiperazin-4-yl)phenol Basic information
- Product Name:
- 4-(1-Acetylpiperazin-4-yl)phenol
- Synonyms:
-
- TIMTEC-BB SBB003353
- N-ACETYL-4-HYDROXYPHENYL PIPERAZINE
- N-ACETYL-4-(4-HYDROXYPHENYL)PIPERAZINE
- 1-Acetyl-4-(4-hydroxyphenyl)piperazine, 98+%
- 1-[4-(4-Hydroxyphenyl)piperazin-1-yl]ethanon
- Piperazine, 1-acetyl-4-(4-hydroxyphenyl)-
- 1-Acetyl-4-(4-Hydroxy-Phenyl)PiperazineKetoconazole
- 4-(4-Acetylpiperazino)phenol
- CAS:
- 67914-60-7
- MF:
- C12H16N2O2
- MW:
- 220.27
- EINECS:
- 267-744-8
- Product Categories:
-
- Piperaizine
- Miscellaneous
- Chemical Amines
- Amines
- Aromatics
- Intermediates & Fine Chemicals
- Chemical intermediate for Ketoconazole
- Piperidines, Piperidones, Piperazines
- Pharmaceuticals
- Building Blocks
- Heterocyclic Building Blocks
- Piperazines
- Mol File:
- 67914-60-7.mol
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4-(1-Acetylpiperazin-4-yl)phenol Chemical Properties
- Melting point:
- 180-185 °C (lit.)
- Boiling point:
- 361.21°C (rough estimate)
- Density
- 1.1115 (rough estimate)
- vapor pressure
- 0Pa at 20℃
- refractive index
- 1.6000 (estimate)
- storage temp.
- -20°C Freezer
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Powder
- pka
- 12.18±0.30(Predicted)
- color
- White to slightly pink or beige
- Water Solubility
- 4.3 g/L (20 ºC)
- BRN
- 795777
- InChIKey
- AGVNLFCRZULMKK-UHFFFAOYSA-N
- LogP
- 0.3
- CAS DataBase Reference
- 67914-60-7(CAS DataBase Reference)
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Safety Information
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-22
- Safety Statements
- 26-36-36/37/39-22
- WGK Germany
- 3
- HS Code
- 29214910
MSDS
- Language:English Provider:1-[4-(4-Hydroxyphenyl)piperazino]ethan-1-one
- Language:English Provider:ACROS
- Language:English Provider:SigmaAldrich
- Language:English Provider:ALFA
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4-(1-Acetylpiperazin-4-yl)phenol Usage And Synthesis
Chemical Properties
Off-White Solid
Uses
1-Acetyl-4-(4-hydroxyphenyl)piperazine may be used in the preparation of 1-acetyl-4-(4-octadecyloxyphenyl)piperazine. It may also be used in the multi-step synthesis of ketoconazole, its 1,2,4-triazole and thiazole analogs.
General Description
1-Acetyl-4-(4-hydroxyphenyl)piperazine (AHPP), a piperazine derivative, is a structural analog of acetaminophen. Its multi-step preparation using bis-(2-chloroethyl)amine hydrochloride and p-aminophenol as starting materials has been reported.2
Flammability and Explosibility
Not classified
4-(1-Acetylpiperazin-4-yl)phenol Preparation Products And Raw materials
Preparation Products
Raw materials
4-(1-Acetylpiperazin-4-yl)phenolSupplier
Conier Chem & Pharma Co.,Ltd, Gold
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- 023-62879767 13996269627;
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Jinan Dexinjia Biological Technology Co., Ltd Gold
- Tel
- 0531-82375809 13210597381
- 1106056172@qq.com
Shanghai Jinhuan Chemical Co.,LTD. Gold
- Tel
- +86-21-52210535 +86-13162045318
- sales@jinhchem.com
BTC Pharmaceutical CO. Ltd Gold
- Tel
- 0513-0513-68015-397-397 15716293042
- sales14@btcpharm.com
J & K SCIENTIFIC LTD.
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
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4-(1-Acetylpiperazin-4-yl)phenol(67914-60-7)Related Product Information
- Acetylacetone
- Phenol Red
- PIPERACETAZINE (250 MG)
- Piperazine
- N-ACETYL-L-TYROSINE ETHYL ESTER
- Acetyl coenzyme A sodium salt
- Acetyl chloride
- 4,4'-Diacetylbiphenyl
- 4-Cyanophenol
- Tetraacetylethylenediamine
- Phenol
- Ketoconazole
- Ketoconazole Impurity 2
- KetoconazoleN-Oxide
- 2-(2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOL-1-YL METHYL)-1,3-DIOXOLANE-4-METHANOL
- Ketoconazole Impurity 4
- cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl-4-methylbenzenesulphonate
- rac-trans-Ketoconazole