Basic information Safety Supplier Related

Lonicerin

Basic information Safety Supplier Related

Lonicerin Basic information

Product Name:
Lonicerin
Synonyms:
  • 7-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-oxan-2-yl]oxy-oxan-2-yl]oxy-2-(3,4-dihydroxyphenyl)-5-hydroxy-chromen-4-one
  • Scolymoside
  • veronicastroside
  • LUTEOLIN-7-RUTINOSIDE
  • LONICERIN
  • Luteolin 7-beta-neohesperidoside
  • Luteolin-7-neohesperidoside
  • Lonicerin Luteolin 7-neohesperidoside
CAS:
25694-72-8
MF:
C27H30O15
MW:
594.52
Mol File:
25694-72-8.mol
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Lonicerin Chemical Properties

Boiling point:
957.8±65.0 °C(Predicted)
Density 
1.76±0.1 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
DMF: 50 mg/ml; DMSO: 50 mg/ml
form 
A crystalline solid
pka
6.08±0.40(Predicted)
color 
Light yellow to yellow
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Lonicerin Usage And Synthesis

Uses

Lonicerin is an anti-algE (alginate secretion protein) flavonoid with inhibitory activity for P. aeruginosa. Lonicerin prevents inflammation and apoptosis in LPS-induced acute lung injury[1][2].

Definition

ChEBI: A disaccharide derivative that is luteolin substituted by a 2-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage.

References

[1] Xu Z, et al. Lonicerin, an anti-algE flavonoid against Pseudomonas aeruginosa virulence screened from Shuanghuanglian formula by molecule docking based strategy. J Ethnopharmacol. 2019 Jul 15;239:111909. DOI:10.1016/j.jep.2019.111909
[2] Lee JH, et al. Antiarthritic effect of lonicerin on Candida albicans arthritis in mice. Arch Pharm Res. 2011 May;34(5):853-9.
[3] Xiao Ding, et al. Evaluation of Anti-MRSA and Xanthine Oxidase Inhibition Activities of Phenolic Constituents from Plumula nelumbinis. Journal of Chemistry. 24 December 2015.

LonicerinSupplier

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