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(R)-1-Boc-3-Hydroxypiperidine

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(R)-1-Boc-3-Hydroxypiperidine Basic information

Product Name:
(R)-1-Boc-3-Hydroxypiperidine
Synonyms:
  • (R)-1-Boc-3-hydroxypiperidine 95%
  • tert-Butyl (3R)-3-hydroxypiperidine-1-carboxylate, (3R)-1-(tert-Butoxycarbonyl)-3-hydroxypiperidine
  • tert- butyl (R)-3-hydroxy piperidine-1-carboxylate
  • (R)-1-Boc-3-hydroxypiperidine,97%
  • (R)-1-N-BOC-3-HYDROXYPIPERIDINE
  • (R)-1-BOC-3-PIPERIDINOL
  • (R)-1-BOC-3-HYDROXYPIPERIDINE
  • R-3-HYDROXY-1-(TERT-BUTOXYCARBONYL)PIPERIDINE
CAS:
143900-43-0
MF:
C10H19NO3
MW:
201.26
Product Categories:
  • Ibrutinib intermediate
  • Piperazine
  • Piperidine
  • Piperidines
Mol File:
143900-43-0.mol
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(R)-1-Boc-3-Hydroxypiperidine Chemical Properties

Melting point:
43-50 °C
Boiling point:
292.3±33.0 °C(Predicted)
Density 
1.107±0.06 g/cm3(Predicted)
Flash point:
104°C
storage temp. 
2-8°C
solubility 
soluble in Methanol
pka
14.74±0.20(Predicted)
form 
Low Melting Solid
color 
White to tan
optical activity
[α]/D 22±3°, c = 5 in methanol
InChIKey
UIJXHKXIOCDSEB-MRVPVSSYSA-N
CAS DataBase Reference
143900-43-0(CAS DataBase Reference)
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Safety Information

Hazard Codes 
T
Risk Statements 
36/37/38-41-37/38-25
Safety Statements 
26-36/37/39-45
RIDADR 
UN 2811 6.1/PG 3
WGK Germany 
3
HazardClass 
6.1
PackingGroup 
HS Code 
29333990
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(R)-1-Boc-3-Hydroxypiperidine Usage And Synthesis

Chemical Properties

White powder

Uses

(R)-1-Boc-3-hydroxypiperidine has been used as a reactant for the synthesis of piperidinyl and pyrrolidinyl butyrates. It has also been used for the synthesis of constrained (-)-S-adenosyl-L-homocysteine (SAH) analogs as DNA methyltransferase inhibitors.

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