MARRUBIIN Chemical Properties

Melting point:

159-162°C

alpha 

D20 +35.8° (c = 3.1 in chloroform); D24 +45° (acetone)

Boiling point:

297-299 °C(Press: 15 Torr)

Density 

1.152±0.06 g/cm3 (20 ºC 760 Torr)

storage temp. 

4°C, protect from light

solubility 

DMSO: 100 mg/mL (300.82 mM)

form 

A solid

pka

14.66±0.70(Predicted)

color 

White to off-white

optical activity

+35.820 (c 3.1, CHCl3)

biological source

plant

LogP

3.400 (est)

Safety Information

Risk Statements 

25

Safety Statements 

1-22-45

RIDADR 

2811

MARRUBIIN Usage And Synthesis

Uses

Marrubiin is an α-glucosidase inhibitor and an analgesic compound.

Definition

ChEBI: Marrubiin is a gamma-lactone.

Biological Activity

Based on existing research, Marrubiin has demonstrated the ability to inhibit the production of pro-inflammatory cytokines and reduce the activity of enzymes involved in oxidative stress. Additionally, it has been observed to lower blood pressure and provide protection against ischemic heart injury.

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