5α-Cholestane
5α-Cholestane Basic information
- Product Name:
- 5α-Cholestane
- Synonyms:
-
- ALPHA, ALPHA, ALPHA 20R-CHOLESTANE
- (5A)-CHOLESTANE
- 5ALPHA-CHOLESTANE
- 10,13-Dimethyl-17-(1',5'-dimethylhexyl)-hexadecahydrocyclopenta(a)phenanthrene
- 28,29,30-Trinorlanostane
- 5A-Cholestane, TMS
- 5-α-cholestane
- alpha-Cholestane
- CAS:
- 481-21-0
- MF:
- C27H48
- MW:
- 372.67
- EINECS:
- 207-562-8
- Product Categories:
-
- CHLipids
- Cholesterol and DerivativesOther Lipid Related Products
- SterolsFood&Beverage Standards
- Alphabetic
- C
- FA/FAME/Lipids/Steroids
- Cholesterol and Derivatives
- Lipids
- Sterols
- Lipid Analytical Standards
- Cholesterol and DerivativesAsymmetric Synthesis
- Chiral Building Blocks
- Complex Molecules
- Mol File:
- 481-21-0.mol
5α-Cholestane Chemical Properties
- Melting point:
- 78-80 °C
- Boiling point:
- 250 °C (1 mmHg)
- Density
- 0.9090
- refractive index
- 1.4887
- storage temp.
- room temp
- form
- Crystalline Powder
- color
- White
- Merck
- 13,2219
- BRN
- 2051806
- LogP
- 11.945 (est)
- CAS DataBase Reference
- 481-21-0(CAS DataBase Reference)
- EPA Substance Registry System
- Cholestane, (5.alpha.)- (481-21-0)
Safety Information
- Hazard Codes
- Xn
- Risk Statements
- 22-38-40-48/20/22-67-36/38-20-63
- Safety Statements
- 24/25-36/37-26
- RIDADR
- UN 1888 6.1/PG 3
- WGK Germany
- 3
- HS Code
- 29021990
MSDS
- Language:English Provider:ACROS
- Language:English Provider:SigmaAldrich
5α-Cholestane Usage And Synthesis
Description
5α-Cholestane is a sterol that has been found in dust samples from urban and rural paved and agricultural and public unpaved roads. It has been used as an internal standard for the quantification of phytosterols by HPLC-MS/MS and fecal sterols by GC-FID and GC-MS.
Chemical Properties
WHITE CRYSTALLINE POWDER
Uses
5α-Cholestane was used as standard in cholesterol analysis by GC and HPLC.
Uses
α-Cholestane is the trans-decalin homolog of Coprostane.
Definition
ChEBI: The 5alpha-stereoisomer of cholestane.
Biochem/physiol Actions
5α-Cholestane is a sterol produced endogenously from cholesterol and has been isolated from human feces. It is derived from cholesterol by the action of intestinal microorganisms. Derivatives of 5α-cholestane in plants are called Brassinosteroids that selectively activate the PPI3K/Akt pathway.
Purification Methods
Crystallise 5-cholestane from Et2O/EtOH or EtOAc. [Ruzicka et al. Helv Chim Acta 16 327 1933, Beilstein 5 III 1132, 5 IV 1227.]
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5α-Cholestane(481-21-0)Related Product Information
- Epibrassinolide
- CHOLESTANE-3β,5α,6β-TRIOL
- 5-ALPHA-CHOLESTANE-B-HOMO-7-OXA-24-BETA-METHYL-2-ALPHA, 3-ALPHA, 22-ALPHA, 23-ALPHA-TETROL-6-ONE
- Chloroform
- Hecogenin
- 3BETA-HYDROXY-5ALPHA-CHOLESTANE,5ALPHA-CHOLESTANE-3BETA-OL
- 5α-Cholestane
- 5alpha-Cholestane-3-one,3-KETO-5ALPHA-CHOLESTANE
- HECOGENIN ACETATE
- Tigogenin
- DIGITONIN
- TOMATINE
- TOMATIDINE
- 5-Hydroxy-5α-cholestane-3,6-dione
- 5ALPHA-CHOLESTANE-3,7-DIONE
- i-Cholestane
- 6β-Methoxy-3α,5-cyclo-5α-cholestane,5-cyclo-5-alpha-cholestane,6-beta-methoxy-3-alp
- TIGOGENIN ACETATE