Methyl 2-hydroxyethyl cellulose Chemical Properties

Density 

1.28-1.30 g/cm3 (20℃)

storage temp. 

Store below +30°C.

solubility 

H₂O: 20 mg/mL, soluble

EPA Substance Registry System

Cellulose, 2-hydroxyethyl methyl ether (9032-42-2)

Safety Information

WGK Germany 

1

Autoignition Temperature

>360 °C

HS Code 

3912 39 85

Toxicity

LD50 orally in Rabbit: > 2000 mg/kg

MSDS

• Language:English Provider:SigmaAldrich

Methyl 2-hydroxyethyl cellulose Usage And Synthesis

Chemical Properties

soluble in cold water, flocculates at elevated temperatures

Chemical Properties

A white, yellowish-white or grayish-white powder or granules, hygroscopic after drying.

Uses

Water retention aid, thickening agent, protective colloid, suspending agent, binder and stabilizer.

Pharmaceutical Applications

Hydroxyethylmethyl cellulose is used as an excipient in a wide range of pharmaceutical products, including oral tablets and suspensions, and topical gel preparations. It has similar properties to methylcellulose, but the hydroxyethyl groups make it more readily soluble in water and solutions are more tolerant of salts and have a higher coagulation temperature.

Safety

Hydroxyethylmethyl cellulose is used as an excipient in various oral and topical pharmaceutical preparations, and is generally regarded as an essentially nontoxic and nonirritant material.

storage

Hydroxyethylmethyl cellulose is hygroscopic and should therefore be stored under dry conditions away from heat.

Regulatory Status

GRAS listed. Included in nonparenteral medicines licensed in Europe (oral suspensions, tablets, and topical preparations).

Methyl 2-hydroxyethyl cellulose(9032-42-2)Related Product Information

• Cellulose acetate
• CELLULOSE
• Ethyl cellulose
• Hydroxyethyl Cellulose
• Methanol
• Acetonitrile
• Microcrystalline cellulose
• CARBOXYMETHYLCELLULOSE SODIUM SALT
• 2-(METHYLSULFONYL)ETHANOL
• DEAE-cellulose
• Methyl
• SALCOMINE
• DICHLORO(ETHYLENEDIAMINE)PLATINUM(II)
• 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE
• N-BUTYLISOCYANIDE
• Tris(2,4-pentanedionato)chroMiuM(III)
• PHENYLSELENOL
• COBALT(II) ACETYLACETONATE