CHRYSOERIOL-7-O-BETA-D-GLUCOSIDE Chemical Properties

Melting point:

176-179℃

Boiling point:

801.6±65.0 °C(Predicted)

Density 

1.609

solubility 

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

form 

powder

pka

6.10±0.40(Predicted)

color 

Yellow

CHRYSOERIOL-7-O-BETA-D-GLUCOSIDE Usage And Synthesis

Uses

Thermopsoside is a flavone derivative isolated from Aspalathus linearis. Thermopsoside exhibits inhibitory effects on CYP450 isozymes with IC50 values of 6.0 μM, 9.5 μM, 12.0 μM, 32.0 μM, for CYP3A4, CYP2C19, CYP2D6 and CYP2C9, respectively[1].

References

[1] Omer I Fantoukh, et al. Safety Assessment of Phytochemicals Derived from the Globalized South African Rooibos Tea ( Aspalathus linearis) through Interaction with CYP, PXR, and P-gp. J Agric Food Chem. 2019 May 1;67(17):4967-4975. DOI:10.1021/acs.jafc.9b00846

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