APST-ZA Chemical Properties

Melting point:

>95°C (dec.)

Boiling point:

673.6±55.0 °C(Predicted)

Density 

1.383±0.06 g/cm3(Predicted)

storage temp. 

Refrigerator, under inert atmosphere

solubility 

Chloroform (Slightly), DMSO (Slightly)

pka

-0.76±0.20(Predicted)

form 

Solid

color 

Off-White to Yellow

APST-ZA Usage And Synthesis

Uses

Des-acetyl Apremilast is the metabolite of Apremilast (A729700), which is an oral phosphodiesterase 4 inhibitor used in the treatment of psoriatic arthritis.

APST-ZA(635705-72-5)Related Product Information

• (R)-N-(2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide
• (S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide
• 2-CHLORO-4'-HYDROXYACETOPHENONE
• Apremilast Impurity 4
• Apremilast
• (S)-N-(2-(1-(3,4-dihydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide
• 6H,12H-Indazolo[2,1-a]indazole-1,7-dicarboxylic acid, 6,12-dioxo-
• 3-oxo-1,3-dihydro-benzo[c]isoxazole-4-carboxylic acid
• Apremilast Impurity 3
• 1,2-Benzenedicarboxylicacid,3-(hydroxyamino)-(9CI)
• Apremilast
• 3,5-Cyclohexadiene-1,2-dione, 4-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]-
• 1H-Indole-3,5,6-triol, 2,3-dihydro-1-(1-methylethyl)- (9CI)
• (S)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethanaMine
• Ipratropium bromide monohydrate
• Ethanone, 2-chloro-1-(3,5-dihydroxyphenyl)-
• Apremilast
• 3-acetamidophthalic acid