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2-chloro-4-(cyclopentylamino)-5-pyrimidinyl ethanone

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2-chloro-4-(cyclopentylamino)-5-pyrimidinyl ethanone Basic information

Product Name:
2-chloro-4-(cyclopentylamino)-5-pyrimidinyl ethanone
Synonyms:
  • 2-chloro-4-(cyclopentylamino)-5-pyrimidinyl ethanone
  • 1-(2-chloro-4-(cyclopentylamino)pyrimidin-5-yl)ethan-1-one
  • Palbociclib Impurity 106
  • Palbociclib impurity 1/1-(2-Chloro-4-(cyclopentylamino)pyrimidin-5-yl)ethan-1-one
  • Ethanone, 1-[2-chloro-4-(cyclopentylamino)-5-pyrimidinyl]-
CAS:
1244949-62-9
MF:
C11H14ClN3O
MW:
239.7
Mol File:
1244949-62-9.mol
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2-chloro-4-(cyclopentylamino)-5-pyrimidinyl ethanone Chemical Properties

Boiling point:
442.1±30.0 °C(Predicted)
Density 
1.305±0.06 g/cm3(Predicted)
pka
0.84±0.10(Predicted)
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2-chloro-4-(cyclopentylamino)-5-pyrimidinyl ethanone Usage And Synthesis

Uses

1-[2-Chloro-4-(cyclopentylamino)-5-pyrimidinyl]ethanone acts as a reagent for the preparation of Palbociclib, a drug for the treatment of ER-positive and HER-negative breast cancer development.

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