Cyanine7 carboxylic acid Chemical Properties

solubility 

Soluble in organic solvents such as DMF

Appearance

Green solid

ex/em

740/770 nm (MeOH/PBS)

ε(extinction coefficient)

199000 L⋅mol−1⋅cm−1

Φ(quantum yield)

0.3

InChIKey

MQMHUMKZLAOASA-UHFFFAOYSA-N

SMILES

C(N1C(C(C)(C)C2=CC=CC=C12)=CC=CC=CC=CC1C(C2=CC=CC=C2[N+]=1C)(C)C)CCCCC(=O)[O-]

Cyanine7 carboxylic acid Usage And Synthesis

Description

The unactivated free carboxylic acid of near-infrared fluorescent dye Cyanine7. For coupling and labeling reactions also consider using pre-activated Cyanine7 NHS ester, or water-soluble sulfo-Cyanine7 NHS ester.

Chemical Properties

Appearance: Green solid
ex/em: 740/770 nm (MeOH/PBS)
Extinction coefficient (ε): 199000 L??mol??1??cm??1
Quantum yield (Φ): 0.3

Uses

Cyanine7 carboxylic acid (Cy7 COOH) is a derivative of Cy7 (HY-D0825) dye. Cyanine7 carboxylic acid contains carboxyl groups, which can condense ammonia to form covalent bonds[1].

References

[1] Zhang X, et al. Highly stable near-infrared dye conjugated cerasomes for fluorescence imaging-guided synergistic chemo-photothermal therapy of colorectal cancer. Biomater Sci. 2019 Jul 1;7(7):2873-2888. DOI:10.1039/c9bm00458k

Abs/Em Maxima

750/773 nm

Extinction Coefficient

199000

CF260

0.022

CF280

0.029

Cyanine7 carboxylic acid(1144107-78-7)Related Product Information

• Cyanine3 NHS ester
• Cyanine5.5 NHS ester
• 1,1'-BIS(4-SULFOBUTYL)-11-(4-ISOTHIOCYANATOPHENYLTHIO)-3,3,3',3'-TETRAMETHYL-10,12-TRI METHYLENEINDOTRICARBOCYANINE MONOSODIUM SALT
• Cy5.5 carboxylic acid
• Cyanine5 amine
• Cyanine5 NHS ester
• Cyclopropene Cyanine 7 amine
• Cyanine5.5 amine
• Cyanine5 carboxylic acid
• Cyanine3.5 NHS ester
• Cy7 Carboxylic acids
• Cyanine3 carboxylic acid
• Cy3.5-COOH
• Cyanine7 NHS ester
• Cyanine7 azide
• Cyanine7 alkyne
• Cyclohexane Cyanine7 NHS
• 1807529-70-9