Forchlorfenuron
Forchlorfenuron Basic information
- Product Name:
- Forchlorfenuron
- Synonyms:
-
- CPPU
- KT-30
- FORCHLORFENURON
- 4-CPPU
- 1-(2-CHLORO-4-PYRIDYL)-3-PHENYLUREA
- 1-(2-CHLOROPYRIDIN-4-YL)-3-PHENYL-UREA
- 4pu30
- cn11-3138
- CAS:
- 68157-60-8
- MF:
- C12H10ClN3O
- MW:
- 247.68
- EINECS:
- 614-346-0
- Product Categories:
-
- plantgrowth
- Agro-Products
- Aromatics
- Heterocycles
- Intermediates & Fine Chemicals
- Pharmaceuticals
- FINE Chemical & INTERMEDIATES
- PLANT GROWTH REGULATOR
- Biochemistry
- Chloropyridines
- Cytokinins
- Halopyridines
- Plant Growth Regulators
- Plant Hormones
- Mol File:
- 68157-60-8.mol
Forchlorfenuron Chemical Properties
- Melting point:
- 170-172°C
- Boiling point:
- 308.4±27.0 °C(Predicted)
- Density
- 1.415±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,2-8°C
- solubility
- Soluble in DMSO or Ethanol
- pka
- 12.55±0.70(Predicted)
- form
- Solid
- color
- White or off-white
- Stability:
- Stable for 1 year from date ofpurchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
- InChI
- InChI=1S/C12H10ClN3O/c13-11-8-10(6-7-14-11)16-12(17)15-9-4-2-1-3-5-9/h1-8H,(H2,14,15,16,17)
- InChIKey
- GPXLRLUVLMHHIK-UHFFFAOYSA-N
- SMILES
- N(C1C=CN=C(Cl)C=1)C(NC1=CC=CC=C1)=O
- CAS DataBase Reference
- 68157-60-8(CAS DataBase Reference)
- EPA Substance Registry System
- Forchlorfenuron (68157-60-8)
Safety Information
- Hazard Codes
- Xi,N,Xn
- Risk Statements
- 36/37-51/53-40
- Safety Statements
- 26-36-61-46-36/37
- RIDADR
- UN3077 9/PG 3
- WGK Germany
- 3
- RTECS
- YS7182500
- HazardClass
- 9
- PackingGroup
- III
- HS Code
- 29333990
- Hazardous Substances Data
- 68157-60-8(Hazardous Substances Data)
- Toxicity
- LD50 oral in mouse: > 500mg/kg
MSDS
- Language:English Provider:SigmaAldrich
Forchlorfenuron Usage And Synthesis
Description
Forchlorfenuron (68157-60-8) reversibly perturbs mammalian septin assembly, organization and function.? Has no effect on actin or tubulin polymerization.1,2 FCF induces effects on mitosis and migration which phenocopy the effects induced by septin depletion using siRNA.1 A useful tool for exploring the physiological role of septin and its complexes.3,4
Chemical Properties
White Solid
Chemical Properties
White to faint yellow crystalline powder.
Uses
Forchlorfenuronis is a diphenylurea-derivative cytokinin. Forchlorfenuronis is used as a plant growth regulator (PGR). Forchlorfenuronis is commonly used in horticulture to stimulate the growth of kiw i fruit and grapes.
Definition
ChEBI: Forchlorfenuron is a member of the class of phenylureas that is urea substituted by a phenyl group and a 2-chloropyridin-4-yl group at positions 1 and 3 respectively. It is a plant growth regulator widely used in agriculture for improving fruit quality and fruit size. It has a role as a plant growth regulator. It is a member of phenylureas and a monochloropyridine.
Agricultural Uses
Plant growth regulator: Forchlorfenuron is as a plant growth regulator to promote cell division, and to improve the quality and the yield of fruits, especially table grapes, grape raisins, and kiwi fruit. In some parts of California, forchlorfenuron is said to double the size of Thompson seedless grapes and delay crop maturity up to several weeks. widely used in agriculture on fruits to increase their size,
Trade name
CN-11-3183; KT-30®; SKW 20010
Potential Exposure
Phenylurea/substituted urea plant growth regulator widely used in agriculture on fruits to increase their size, to promote cell division, and to improve the quality and the yield of fruits, especially table grapes, grape raisins, and kiwi fruit. In some parts of California, forchlorfenuron is reputed to double the size of Thompson seedless grapes and delay crop maturity up to several weeks.
Shipping
UN2767 Phenyl urea pesticides, solid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.
Incompatibilities
May react with strong oxidizers such as chlorates, peroxides, nitrates, etc. Dust may form explosive mixture with air.
Waste Disposal
Containers must be disposed of properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office. If this material cannot be disposed of according to label instruc tions, it may be dissolved or mixed with a combustible sol vent and burned in a chemical incinerator equipped with an afterburner and scrubber. In accordance with 40CFR165, follow recommendations for the disposal of pesticides and pesticide containers.
References
1) Hu et al. (2008), Forchlorfenuron alters mammalian septin assembly, organization, and dynamics; J. Biol. Chem., 283 29563 2) DeMay et al. (2010), Cellular requirements for the small molecule forchlorfenuron to stabilize the septin cytoskeleton; Cytoskeleton, 67 383 3) Wasik et al. (2012), Septin 7 forms a complex with CD2AP and nephrin and regulates glucose transporter trafficking; Mol. Biol. Cell, 23 3370 4) Vardi-Oknin et al. (2013), Forchlorfenuron disrupts SEPT9_i1 filaments and inhibits HIF-1; PLoS One, 8(8) e73179
Forchlorfenuron Preparation Products And Raw materials
Raw materials
ForchlorfenuronSupplier
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