ChemicalBook > Product Catalog > Biochemical Engineering > Amino Acids and Derivatives > Other Amino Acid Protection > TBTU
TBTU
TBTU Basic information
- Product Name:
- TBTU
- Synonyms:
-
- benzotriazol-1-yl-tetramethyluroniumtetrafluoroborate
- [benzotriazol-1-yloxy(dimethylamino)methylene]-dimethyl-ammonium
- 1-[Bis(dimethylamino)methylene]-1H-benzotriazolium 3-Oxide Tetrafluoroborate
- O-(1H-BENZOTRIAZOL-1-YL)-N,N,N',N'-TETRAMETHYLURONIUM TETRAFLUOROBORATE
- O-(1H-BENZOTRIAZOLE-1-YL) N,N,N',N'-TETRAMETHYL URONIUM TETRAFLUOROBORATE
- O-(1H-BENZOTRIAZOL-1-YL)-1,1,3,3-TETRAMETHYL-URONIUM TETRAFLUOROBORATE
- O-(1H-BENZOTRIAZOL-1-YL)-N,N,N',N'-PENTAMETHYLENE-URONIUM TETRAFLUOROBORATE
- O-(1H-BENZO-1,2,3-TRIAZOL-1-YL)-N,N,N',N'-TETRAMETHYL-URONIUM TETRAFLUOROBORATE
- CAS:
- 125700-67-6
- MF:
- C11H16BF4N5O
- MW:
- 321.09
- EINECS:
- 603-087-9
- Product Categories:
-
- Peptide Coupling Reagents
- B (Classes of Boron Compounds)
- Biochemistry
- Condensation & Active Esterification
- Coupling Reactions (Peptide Synthesis)
- Peptide Synthesis
- Synthetic Organic Chemistry
- Tetrafluoroborates
- Peptide
- Coupling Reagent
- PROTECTED AMINO ACID & PEPTIDES
- Amino Acid Derivatives
- 125700-67-6
- Mol File:
- 125700-67-6.mol
More
Less
TBTU Chemical Properties
- Melting point:
- 205 °C (dec.)(lit.)
- storage temp.
- 2-8°C
- solubility
- acetonitrile: 0.1 g/mL, clear
- form
- Powder
- color
- White to Almost white
- Water Solubility
- Soluble in acetonitrile (100 mg/ml, clear, colorless), DMF (160.55 mg/ml, clear), and water (3 mg/ml at 20°C).
- Sensitive
- Moisture Sensitive
- BRN
- 7066325
- InChI
- InChI=1S/C11H16N5O.BF4/c1-13(2)11(14(3)4)15-9-7-5-6-8-10(9)16(17)12-15;2-1(3,4)5/h5-8H,1-4H3;/q+1;-1
- InChIKey
- NQGZJNPFMLJDKU-UHFFFAOYSA-M
- SMILES
- [B+3]([F-])([F-])([F-])[F-].C(=[N+]1/N=N(=O)C2=CC=CC=C/12)(\N(C)C)/N(C)C
- LogP
- -2.65 at 21℃
- CAS DataBase Reference
- 125700-67-6(CAS DataBase Reference)
- EPA Substance Registry System
- 1H-Benzotriazolium, 1-[bis(dimethylamino)methylene]-, 3-oxide, tetrafluoroborate(1-) (1:1) (125700-67-6)
More
Less
Safety Information
- Hazard Codes
- Xi,F,E
- Risk Statements
- 36/37/38-5-2
- Safety Statements
- 26-36-37/39-36/37/39-35
- RIDADR
- 1325
- WGK Germany
- 3
- F
- 8-10-21
- Hazard Note
- Irritant/Flammable
- HS Code
- 2933 99 80
- HazardClass
- 4.1
- PackingGroup
- Ⅱ
MSDS
- Language:English Provider:SigmaAldrich
- Language:English Provider:ALFA
More
Less
TBTU Usage And Synthesis
Chemical Properties
TBTU [chemical name:2-(1H-Benzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate] is WHITE TO PALE CREAM FINE CRYSTALLINE POWDER
Uses
TBTU is a coupling reagent for peptide synthesis causing low racemization, which is ideally suited for solid-phase peptide synthesis. Also used in the synthesis of acid based t-antigen glycodendrimers.
reaction suitability
reaction type: Coupling Reactions
TBTU Preparation Products And Raw materials
Preparation Products
TBTUSupplier
Suzhou Highfine Biotech Co., Ltd Gold
- Tel
- 0512-69209928 18796809688
- zhouyingxiang@highfine.com
Changzhow Moisten International Trading Co., Ltd. Gold
- Tel
- 13606112397
- tang13606112397@163.com
Shanghai Zhuorui Chemical Co.,Ltd. Gold
- Tel
- 021-69180038
- zhuoruichem@163.com
Lianyungang Guanxin Pharmaceutical Technology Co., Ltd Gold
- Tel
- 15351860687
- 1462699602@qq.com
Jiangsu Jitai Peptide Technology Co., Ltd. Gold
- Tel
- 0515-8085-5066 13770132022
- sales05@gtaipeptide.com
More
Less
TBTU(125700-67-6)Related Product Information
- Tolyltriazole
- AZURE B TETRAFLUOROBORATE
- 1,1,3,3-Tetramethylurea
- 1H-Benzotriazole
- 5-Methyl-1H-benzotriazole
- Ribavirin
- 1,2,3-1H-Triazole
- O-(6-Chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate
- 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride
- 3-Hydroxy-1,2,3-benzotriazin-4(3H)-one
- 2-(7-Azabenzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate
- HOAt
- 1-Hydroxybenzotriazole
- HBTU
- HATU
- Fluoroboric acid
- TBTU
- 1-Hydroxybenzotriazole hydrate