(-)-DIOP Chemical Properties

Melting point:

88-90 °C(lit.)

alpha 

-26° (c 2.0, CHCl3)

Boiling point:

590.3±25.0 °C(Predicted)

storage temp. 

2-8°C

form 

Powder

color 

white

optical activity

[α]19/D 26°, c = 2.3 in chloroform

Sensitive 

Air Sensitive

BRN 

1441045

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36/37

WGK Germany 

3

F 

10-23

TSCA 

No

HS Code 

29329990

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

(-)-DIOP Usage And Synthesis

Chemical Properties

white powder

Uses

For the in situ preparation of chiral hydrogenation catalysts.

General Description

(-)-2,3-O-Isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosphino)butane is a C₂ chelating diphosphine ligand for transition metal complexes during asymmetric catalysis.

Purification Methods

It has been recrystallised from *C6H6/pet ether. After 2 recrystallisations from EtOH, it was pure by TLC on silica gel using Me2CO/hexane as solvent. [Kagan & Dang J Am Chem Soc 94 6429 1972.] Lanthanide shift reagents See in “Aliphatic Compounds”, Chapter 4, europium (III) acetate above and Eu(tmc)3 and Eu(tfc)3 below.

(-)-DIOP(32305-98-9)Related Product Information

• Isopropenylboronic acid pinacol ester
• (-)-Taddol
• ISOPROPENYLMAGNESIUM BROMIDE
• Flexol plasticizer diop
• (+)-DIOP,(S,S)-DIOP,(4S,5S)-(+)-4,5-Bis(diphenylphosphinomethyl)-2,2-dimethyl-1,3-dioxolane,99.5%(S,S)-DIOP
• (-)-DIOP
• 1,4-Bis(diphenylphosphino)butane
• 1,3-Dioxolane
• 2,2,4-TRIMETHYL-1,3-DIOXOLANE
• 2,2-Diethoxypropane
• Diphenylphosphine
• (2R,3R)-(+)-BIS(DIPHENYLPHOSPHINO)BUTANE
• 2,2-DIMETHYL-1,3-DIOXOLANE
• 2-METHYL-1,3-DIOXOLANE
• 2,4-DIMETHYL, 1,3-DIOXALONE
• BUTYLDIPHENYLPHOSPHINE
• 1,4-BIS(DIMETHYLPHOSPHINO)BUTANE
• (+)-MOD-DIOP