2-(Butylamino)ethanol Chemical Properties

Melting point:

28.94°C (estimate)

Boiling point:

198-200 °C(lit.)

Density 

0.891 g/mL at 25 °C(lit.)

vapor pressure 

13.94Pa at 20℃

refractive index 

n20/D 1.444(lit.)

Flash point:

170 °F

storage temp. 

2-8°C

solubility 

1000g/l

form 

clear liquid

pka

14.81±0.10(Predicted)

Specific Gravity

0.893

color 

Colorless to Almost colorless

PH

11.9 (100g/l, H2O, 20℃)

explosive limit

1.5-8.6%(V)

biological source

goat

Water Solubility 

1000g/L at 20℃

BRN 

1732522

Cosmetics Ingredients Functions

BUFFERING

InChI

1S/C6H15NO/c1-2-3-4-7-5-6-8/h7-8H,2-6H2,1H3

InChIKey

LJDSTRZHPWMDPG-UHFFFAOYSA-N

SMILES

CCCCNCCO

LogP

0.64 at 25℃

CAS DataBase Reference

111-75-1(CAS DataBase Reference)

EPA Substance Registry System

Ethanol, 2-(butylamino)- (111-75-1)

Safety Information

Hazard Codes 

C

Risk Statements 

22-34

Safety Statements 

26-36/37/39-45

RIDADR 

UN 2735 8/PG 2

WGK Germany 

1

RTECS 

KK0175000

TSCA 

TSCA listed

HazardClass 

8

PackingGroup 

II

HS Code 

29221990

Storage Class

8A - Combustible corrosive hazardous materials

Hazard Classifications

Acute Tox. 4 Oral
Eye Dam. 1
Skin Corr. 1B

MSDS

• Language:English Provider:SigmaAldrich

2-(Butylamino)ethanol Usage And Synthesis

Description

2-(butylamino)ethanol (BAE) is a secondary amine and has steric hindrance with a strong tendency to form bicarbonate on reaction with CO2. As a result, equilibrium CO2 loading can exceed 0.5 mol CO2/mol amine, resulting in higher cyclic capacity than conventional MEA. BAE's hydrophobicity is very high and highly soluble with most amines and ethers. The advantages of preferring BAE over traditional 2-amino-2-methyl-1-propanol (AMP) are that BAE does not produce solid precipitation on CO2 loading, CO2 absorption and reaction rate of BAE is higher than AMP, it can be regenerated at low temperature, low heat of CO2 absorption and BAE is cheaper than AMP[1].

Chemical Properties

Colorless liquid

Uses

2-(Butylamino)ethanol (N-Butylethanolamine) may be employed for the synthesis of 4-alkylamino-2,5,6-trimethyl -7-(2,4,6-trimethylphenyl)pyrrolo[2,3-d]pyrimidines and N-butyl-N-(2-nitroxyethyl)nitramine (BuNENA).

General Description

2-(Butylamino)ethanol is a secondary amine having a -OH group.

Safety Profile

Moderately toxic by ingestion and intraperitoneal routes. A skin and severe eye irritant. See also AMINES. Combustible when exposed to heat or flame. To fight fire, use alcohol foam, foam, Con, dry chemical. Incompatible with oxihzing materials. When heated to decomposition it emits toxic fumes of NOx

Synthesis

To a solution of 3-aminopropan-1-ol (1.0 g, 13.3 mmol) and propionaldehyde (0.77 g, 13.3 mmol) in MeOH (20 mL) was added MgSO4 (6.4 g, 53.3 mmol). The reaction mixture was stirred at 25 ??C for 12 h. The undissolved material was filtered and the filtrate was treated with NaBH4 (556 mg, 14.6 mmol) under an ice bath. The mixture was then stirred at 25 ??C for 1 hour. The reaction solution was concentrated in vacuum and the residue was dissolved in DCM (100 mL) and stirred for 5 min. The undissolved material was filtered and the filtrate was concentrated in vacuum to give 2-butylaminoethanol (1.0 g, 64.1%) as a yellow oil.

Toxics Screening Level

The Initial Risk Screening Level (ITSL) for 2-Butylaminoethanol is 4 μg/m3 based on annual averaging time.

References

[1] Ashish Gautam, Monoj Kumar Mondal. “Novel aqueous amine blend of 2-(Butylamino)ethanol and 2-Dimethylaminoethanol for CO2 capture: Equilibrium CO2 loading, RSM optimization, desorption study, characterization and toxicity assessment.” Separation and Purification Technology 322 (2023): Article 124279.

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