2-Chloro-4-fluorobenzoic acid Chemical Properties

Melting point:

181-183 °C (lit.)

Boiling point:

271.9±20.0 °C(Predicted)

Density 

1.4016 (estimate)

storage temp. 

Sealed in dry,Room Temperature

solubility 

95% ethanol: soluble50mg/mL, clear to very slightly hazy, colorless to very faintly yellow

pka

2.90±0.25(Predicted)

form 

Powder or Flakes

color 

White

BRN 

1946215

InChI

InChI=1S/C7H4ClFO2/c8-6-3-4(9)1-2-5(6)7(10)11/h1-3H,(H,10,11)

InChIKey

GRPWQLDSGNZEQE-UHFFFAOYSA-N

SMILES

C(O)(=O)C1=CC=C(F)C=C1Cl

CAS DataBase Reference

2252-51-9(CAS DataBase Reference)

NIST Chemistry Reference

2-Chloro-4-fluorobenzoic acid(2252-51-9)

EPA Substance Registry System

Benzoic acid, 2-chloro-4-fluoro- (2252-51-9)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

22-37/38-41-36/37/38

Safety Statements 

26-36/37/39-37/39-36

WGK Germany 

3

HazardClass 

IRRITANT

HS Code 

29163990

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

2-Chloro-4-fluorobenzoic acid Usage And Synthesis

Chemical Properties

Powder or crystalline or flakes

Uses

2-Chloro-4-fluorobenzoic acid was used in the preparation of 2-(2-chloro-4-fluorophenyl)-benzothiazole.

Application

2-Chloro-4-fluorobenzoic acid can be used as:
(1) Studies on the preparation, luminescence and thermal properties of lanthanide complexes of 2-chloro-4-fluorobenzoic acid.
(2) Preparation, crystal structure, thermal and fluorescence property studies of rare earth complexes composed with 2,2':6′,2″-tripyridine.
(3) Analysis of charge density of intermolecular interactions between isohalogen (Cl--F) and homohalogen (F--F) molecules in molecular crystals. Attractive intermolecular Cl--F interactions (type II interactions) in 2-chloro-4-fluorobenzoic acid.

2-Chloro-4-fluorobenzoic acid(2252-51-9)Related Product Information

• Isobutyl chloroformate
• 2-Amino-4-fluorobenzoic acid
• 3-Chloroperoxybenzoic acid
• 4-(4-Fluorobenzoyl)butyric acid
• 2-Chloro-4-fluorophenol
• (+)-MENTHYL CHLOROFORMATE
• Pentyl chloroformate
• 4-Fluorobenzamide
• 4-Fluorobenzoic acid
• 4-(Chloromethyl)benzoic acid
• Phthalic acid
• 2,4,5-Trifluorobenzoic acid
• 2,6-Difluorobenzoic acid
• Bis(2-ethylhexyl) phthalate
• 1,2-Difluorobenzene
• Benzyl chloroformate
• 2-Chloro-4-fluorobenzonitrile
• 4-Bromo-2-fluorobenzoic acid