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4-METHOXY-3-HYDROXYACETOPHENONE

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4-METHOXY-3-HYDROXYACETOPHENONE Basic information

Product Name:
4-METHOXY-3-HYDROXYACETOPHENONE
Synonyms:
  • Acetoisovanillone
  • 1-(3-hydroxy-4-Methoxyphenyl)ethan-1-one
  • Ethanone, 1-(3-hydroxy-4-Methoxyphenyl)-
  • 5-Acetyl-2-methoxyphenol
  • Isoacetovanillone
  • NSC 30050
  • ACETOISOVANILLONE(SH)
  • 3-HYDROXY-4-METHOXYACETOPHENONE
CAS:
6100-74-9
MF:
C9H10O3
MW:
166.17
Product Categories:
  • Aromatic Acetophenones & Derivatives (substituted)
Mol File:
6100-74-9.mol
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4-METHOXY-3-HYDROXYACETOPHENONE Chemical Properties

Melting point:
88-92 °C
Boiling point:
329.9±27.0 °C(Predicted)
Density 
1.158
storage temp. 
Inert atmosphere,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
9.15±0.10(Predicted)
color 
Off-White to Yellow
Stability:
Stable. Incompatible with strong oxidizing agents.
LogP
1.373 (est)
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Safety Information

Hazard Codes 
Xn
Risk Statements 
22
WGK Germany 
3
HS Code 
2914390090
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4-METHOXY-3-HYDROXYACETOPHENONE Usage And Synthesis

Chemical Properties

solid

Uses

Isoacetovanillone (Diosmin EP Impurity A) is a volatile compound isolated from oak wood. Also a byproduct in the production of Acetovanillone.

Uses

Isoacetovanillone is a volatile compound isolated from oak wood. Also a byproduct in the production of Acetovanillone.

Definition

ChEBI: Isoacetovanillone is a member of phenols and a member of methoxybenzenes. It has a role as a metabolite.

Preparation

Preparation by saponification of 3-acetoxy-4-methoxy-acetophenone (90%) (59%).

Synthesis Reference(s)

Synthetic Communications, 18, p. 1379, 1988 DOI: 10.1080/00397918808078806

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