2-Aminocyclohexanol Chemical Properties

Melting point:

65 °C

Boiling point:

212 °C

Density 

1.037±0.06 g/cm3(Predicted)

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

solubility 

soluble in Methanol

form 

powder to crystal

pka

14.94±0.40(Predicted)

color 

White to Light orange to Yellow

InChIKey

PQMCFTMVQORYJC-UHFFFAOYSA-N

CAS DataBase Reference

6850-38-0(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi,Xn

Risk Statements 

34-22

Safety Statements 

26-36/37/39

RIDADR 

3259

Hazard Note 

Irritant

HazardClass 

8

PackingGroup 

III

HS Code 

2922190090

2-Aminocyclohexanol Usage And Synthesis

Chemical Properties

White to Light orange to Yellow powder to crystal.

Uses

Trans-2-aminocyclohexanol and cis-/trans-1,2-cyclohexanediamines have found their application in the synthesis of the antiarrhythmic medicament vernakalant and spleen tyrosine kinase inhibitor, κ-opioid analgesics.

Preparation

2-Aminocyclohexanol Synthesis: Under water bath reaction conditions, 214.3 g of ammonia water was added to a 500 mL three-necked flask. Stir and heat, and when the internal temperature reaches about 50°C, start to slowly drop 50.0 g of 1,2-epoxycyclohexane into the reaction flask. After the dropwise addition was completed, the reaction was performed at a constant temperature for 12h. After the reaction was completed, the reaction was processed to obtain a crude product, which was purified by recrystallization to obtain 2-aminocyclohexanol with a yield of 90% and an amine value (mgKOH/g) of 453.

2-Aminocyclohexanol(6850-38-0)Related Product Information

• EC 2.6.1.2
• Cyclohexanone
• Tris(hydroxymethyl)aminomethane
• Acetaminophen
• Cyclohexanol
• Molasses
• SPECTINOMYCIN DIHYDROCHLORIDE
• RIBOSTAMYCIN SULFATE SALT
• (1'R,3'S,3S,5R,6R)-5-AMINO-2-AMINOMETHYL-6-(4,6-DIAMINO-2,3-DIHYDROXY-CYCLOHEXYLOXY)-TETRAHYDRO-PYRAN-3,4-DIOL
• Sisomicin
• TRANS-2-AMINOCYCLOHEXANOL HYDROCHLORIDE
• Amino alcohol
• trans-4-Aminocyclohexanol
• Neomycin sulfate
• KANAMYCIN
• Gentamicin
• Spectinomycin
• 4-Aminocyclohexanol